Functional Domain Order of an Anti-EGFR × Anti-CD16 Bispecific Diabody Involving NK Cell Activation

by Atsushi Kuwahara, Keisuke Nagai, Takeshi Nakanishi, Izumi Kumagai, Ryutaro Asano
Published 2020-11-01

Chemically Crosslinked Bispecific Antibodies for Cancer Therapy: Breaking from the Structural Restrictions of the Genetic Fusion Approach

by Asami Ueda, Mitsuo Umetsu, Takeshi Nakanishi, Kentaro Hashikami, Hikaru Nakazawa, Shuhei Hattori, Ryutaro Asano, Izumi Kumagai
Published 2020-01-01

A semi high-throughput method for screening small bispecific antibodies with high cytotoxicity

by Aruto Sugiyama, Mitsuo Umetsu, Hikaru Nakazawa, Teppei Niide, Tomoko Onodera, Katsuhiro Hosokawa, Shuhei Hattori, Ryutaro Asano, Izumi Kumagai
Published 2017-06-01

Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope

by Koki Makabe, Takeshi Yokoyama, Shiro Uehara, Tomomi Uchikubo-Kamo, Mikako Shirouzu, Kouki Kimura, Kouhei Tsumoto, Ryutaro Asano, Yoshikazu Tanaka, Izumi Kumagai
Published 2021-03-01