From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation

by Carlotta Cecchini, Carlotta Cecchini, Sara Pannilunghi, Sara Pannilunghi, Sébastien Tardy, Sébastien Tardy, Leonardo Scapozza, Leonardo Scapozza
Published 2021-04-01

Exploring the Ubiquitin-Proteasome System (UPS) through PROTAC Technology

by Carlotta Cecchini, Sébastien Tardy, Valentina Ceserani, Jean-Philippe Theurillat, Leonardo Scapozza
Published 2020-04-01

Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation

by Olivier Preynat-Seauve, Olivier Preynat-Seauve, Evelyne Bao-Vi Nguyen, Yvonne Westermaier, Margaux Héritier, Sébastien Tardy, Yves Cambet, Maxime Feyeux, Aurélie Caillon, Leonardo Scapozza, Karl-Heinz Krause, Karl-Heinz Krause
Published 2021-08-01

Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of Lasiodiplodia venezuelensis

by Léonie Pellissier, Léonie Pellissier, Alexey Koval, Laurence Marcourt, Laurence Marcourt, Emerson Ferreira Queiroz, Emerson Ferreira Queiroz, Nicole Lecoultre, Sara Leoni, Luis-Manuel Quiros-Guerrero, Luis-Manuel Quiros-Guerrero, Morgane Barthélémy, Bastiaan L. Duivelshof, Bastiaan L. Duivelshof, Davy Guillarme, Davy Guillarme, Sébastien Tardy, Sébastien Tardy, Véronique Eparvier, Karl Perron, Karl Perron, Jérôme Chave, Didier Stien, Katia Gindro, Vladimir Katanaev, Vladimir Katanaev, Jean-Luc Wolfender, Jean-Luc Wolfender
Published 2021-08-01