AGEs induce ectopic endochondral ossification in intervertebral discs

by S Illien-Jünger, OM Torre, WF Kindschuh, X Chen, DM Laudier, JC Iatridis
Published 2016-11-01

The Application of Mesenchymal Stromal Cells and Their Homing Capabilities to Regenerate the Intervertebral Disc

by Andreas S. Croft, Svenja Illien-Jünger, Sibylle Grad, Julien Guerrero, Sebastian Wangler, Benjamin Gantenbein
Published 2021-03-01

Leptin signaling and the intervertebral disc: Sex dependent effects of leptin receptor deficiency and Western diet on the spine in a type 2 diabetes mouse model.

by Devorah M Natelson, Alon Lai, Divya Krishnamoorthy, Robert C Hoy, James C Iatridis, Svenja Illien-Jünger
Published 2020-01-01

Combined anti-inflammatory and anti-AGE drug treatments have a protective effect on intervertebral discs in mice with diabetes.

by Svenja Illien-Junger, Fabrizio Grosjean, Damien M Laudier, Helen Vlassara, Gary E Striker, James C Iatridis
Published 2013-01-01

Fibrin-genipin adhesive hydrogel for annulus fibrosus repair: performance evaluation with large animal organ culture, in situ biomechanics, and in vivo degradation tests

by M Likhitpanichkul, M Dreischarf, S Illien-Junger, BA Walter, T Nukaga, RG Long, D Sakai, AC Hecht, JC Iatridis
Published 2014-07-01

TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs.

by Benjamin A Walter, Morakot Likhitpanichkul, Svenja Illien-Junger, Peter J Roughley, Andrew C Hecht, James C Iatridis
Published 2015-01-01

Dietary advanced glycation end-product consumption leads to mechanical stiffening of murine intervertebral discs

by Divya Krishnamoorthy, Robert C. Hoy, Devorah M. Natelson, Olivia M. Torre, Damien M. Laudier, James C. Iatridis, Svenja Illien-Jünger
Published 2018-12-01

Chronic ingestion of advanced glycation end products induces degenerative spinal changes and hypertrophy in aging pre-diabetic mice.

by Svenja Illien-Jünger, Young Lu, Sheeraz A Qureshi, Andrew C Hecht, Weijing Cai, Helen Vlassara, Gary E Striker, James C Iatridis
Published 2015-01-01

Development of a standardized histopathology scoring system for human intervertebral disc degeneration: an Orthopaedic Research Society Spine Section Initiative

by Christine L. Le Maitre, Chitra L. Dahia, Morgan Giers, Svenja Illien‐Junger, Claudia Cicione, Dino Samartzis, Gianluca Vadala, Aaron Fields, Jeffrey Lotz
Published 2021-06-01