Codon usage optimization in pluripotent embryonic stem cells

by Susanne Bornelöv, Tommaso Selmi, Sophia Flad, Sabine Dietmann, Michaela Frye
Published 2019-06-01

Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum

by Jamie A. Hackett, Toshihiro Kobayashi, Sabine Dietmann, M. Azim Surani
Published 2017-06-01

A conceptual and computational framework for modelling and understanding the non-equilibrium gene regulatory networks of mouse embryonic stem cells.

by Richard B Greaves, Sabine Dietmann, Austin Smith, Susan Stepney, Julianne D Halley
Published 2017-09-01

RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin

by Roberto Bandiera, Rebecca E. Wagner, Thiago Britto-Borges, Christoph Dieterich, Sabine Dietmann, Susanne Bornelöv, Michaela Frye
Published 2021-10-01

G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

by Jan J Zylicz, Maud Borensztein, Frederick CK Wong, Yun Huang, Caroline Lee, Sabine Dietmann, M Azim Surani
Published 2018-05-01

Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development

by Jan J Zylicz, Sabine Dietmann, Ufuk Günesdogan, Jamie A Hackett, Delphine Cougot, Caroline Lee, M Azim Surani
Published 2015-11-01

Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia

by Philip W. Brownjohn, James Smith, Ravi Solanki, Ebba Lohmann, Henry Houlden, John Hardy, Sabine Dietmann, Frederick J. Livesey
Published 2018-04-01

A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons

by Anastasiya Sybirna, Walfred W. C. Tang, Merrick Pierson Smela, Sabine Dietmann, Wolfram H. Gruhn, Ran Brosh, M. Azim Surani
Published 2020-03-01

High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures

by Kyaw Thu Minn, Yuheng C Fu, Shenghua He, Sabine Dietmann, Steven C George, Mark A Anastasio, Samantha A Morris, Lilianna Solnica-Krezel
Published 2020-11-01

Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation

by Abdulrahim A. Sajini, Nila Roy Choudhury, Rebecca E. Wagner, Susanne Bornelöv, Tommaso Selmi, Christos Spanos, Sabine Dietmann, Juri Rappsilber, Gracjan Michlewski, Michaela Frye
Published 2019-06-01

NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

by Shobbir Hussain, Abdulrahim A. Sajini, Sandra Blanco, Sabine Dietmann, Patrick Lombard, Yoichiro Sugimoto, Maike Paramor, Joseph G. Gleeson, Duncan T. Odom, Jernej Ule, Michaela Frye
Published 2013-07-01

Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening

by Shafqat A. Khan, Kyoung-mi Park, Laura A. Fischer, Chen Dong, Tenzin Lungjangwa, Marta Jimenez, Dominick Casalena, Brian Chew, Sabine Dietmann, Douglas S. Auld, Rudolf Jaenisch, Thorold W. Theunissen
Published 2021-06-01

Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage

by Qifan Zhu, Fei Sang, Sarah Withey, Walfred Tang, Sabine Dietmann, Doris Klisch, Priscila Ramos-Ibeas, Haixin Zhang, Cristina E. Requena, Petra Hajkova, Matt Loose, M. Azim Surani, Ramiro Alberio
Published 2021-02-01

Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency

by Nicholas Bredenkamp, Jian Yang, James Clarke, Giuliano Giuseppe Stirparo, Ferdinand von Meyenn, Sabine Dietmann, Duncan Baker, Rosalind Drummond, Yongming Ren, Dongwei Li, Chuman Wu, Maria Rostovskaya, Sarah Eminli-Meissner, Austin Smith, Ge Guo
Published 2019-12-01

Cytosine-5 RNA methylation links protein synthesis to cell metabolism.

by Nikoletta A Gkatza, Cecilia Castro, Robert F Harvey, Matthias Heiß, Martyna C Popis, Sandra Blanco, Susanne Bornelöv, Abdulrahim A Sajini, Joseph G Gleeson, Julian L Griffin, James A West, Stefanie Kellner, Anne E Willis, Sabine Dietmann, Michaela Frye
Published 2019-06-01

Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3

by Lindsey Van Haute, Sabine Dietmann, Laura Kremer, Shobbir Hussain, Sarah F. Pearce, Christopher A. Powell, Joanna Rorbach, Rebecca Lantaff, Sandra Blanco, Sascha Sauer, Urania Kotzaeridou, Georg F. Hoffmann, Yasin Memari, Anja Kolb-Kokocinski, Richard Durbin, Johannes A. Mayr, Michaela Frye, Holger Prokisch, Michal Minczuk
Published 2016-06-01

OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human

by Xin Huang, Kyoung-mi Park, Paul Gontarz, Bo Zhang, Joshua Pan, Zachary McKenzie, Laura A. Fischer, Chen Dong, Sabine Dietmann, Xiaoyun Xing, Pavel V. Shliaha, Jihong Yang, Dan Li, Junjun Ding, Tenzin Lungjangwa, Maya Mitalipova, Shafqat A. Khan, Sumeth Imsoonthornruksa, Nick Jensen, Ting Wang, Cigall Kadoch, Rudolf Jaenisch, Jianlong Wang, Thorold W. Theunissen
Published 2021-08-01