In vitro activity of SPR719 against Mycobacterium ulcerans, Mycobacterium marinum and Mycobacterium chimaera.

by Sacha J Pidot, Jessica L Porter, Troy Lister, Timothy P Stinear
Published 2021-07-01

Mycobacterium ulcerans and other mycolactone-producing mycobacteria should be considered a single species.

by Sacha J Pidot, Kingsley Asiedu, Michael Käser, Janet A M Fyfe, Timothy P Stinear
Published 2010-01-01

Analysis of the vaccine potential of plasmid DNA encoding nine mycolactone polyketide synthase domains in Mycobacterium ulcerans infected mice.

by Virginie Roupie, Sacha J Pidot, Tobba Einarsdottir, Christophe Van Den Poel, Fabienne Jurion, Timothy P Stinear, Kris Huygen
Published 2014-01-01

The cell wall-associated mycolactone polyketide synthases are necessary but not sufficient for mycolactone biosynthesis.

by Jessica L Porter, Nicholas J Tobias, Sacha J Pidot, Steffen Falgner, Kellie L Tuck, Andrea Vettiger, Hui Hong, Peter F Leadlay, Timothy P Stinear
Published 2013-01-01

The ΦBT1 large serine recombinase catalyzes DNA integration at pseudo-attB sites in the genus Nocardia

by Marion Herisse, Jessica L. Porter, Romain Guerillot, Takehiro Tomita, Anders Goncalves Da Silva, Torsten Seemann, Benjamin P. Howden, Timothy P. Stinear, Sacha J. Pidot
Published 2018-05-01

Single nucleotide polymorphism typing of Mycobacterium ulcerans reveals focal transmission of buruli ulcer in a highly endemic region of Ghana.

by Katharina Röltgen, Weihong Qi, Marie-Thérèse Ruf, Ernestina Mensah-Quainoo, Sacha J Pidot, Torsten Seemann, Timothy P Stinear, Michael Käser, Dorothy Yeboah-Manu, Gerd Pluschke
Published 2010-01-01

Mining the Methylome Reveals Extensive Diversity in Staphylococcus epidermidis Restriction Modification

by Jean Y. H. Lee, Glen P. Carter, Sacha J. Pidot, Romain Guérillot, Torsten Seemann, Anders Gonçalves da Silva, Timothy J. Foster, Benjamin P. Howden, Timothy P. Stinear, Ian R. Monk
Published 2019-12-01

High antibody titres induced by protein subunit vaccines using Mycobacterium ulcerans antigens Hsp18 and MUL_3720 with a TLR-2 agonist fail to protect against Buruli ulcer in mice

by Kirstie M. Mangas, Nicholas J. Tobias, Estelle Marion, Jérémie Babonneau, Laurent Marsollier, Jessica L. Porter, Sacha J. Pidot, Chinn Yi Wong, David C. Jackson, Brendon Y. Chua, Timothy P. Stinear
Published 2020-08-01

Mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer.

by John R Wallace, Kirstie M Mangas, Jessica L Porter, Renee Marcsisin, Sacha J Pidot, Brian Howden, Till F Omansen, Weiguang Zeng, Jason K Axford, Paul D R Johnson, Timothy P Stinear
Published 2017-04-01

Multi-Omic Analysis of Symbiotic Bacteria Associated With Aedes aegypti Breeding Sites

by Katherine D. Mosquera, Luis E. Martinez Villegas, Luis E. Martinez Villegas, Sacha J. Pidot, Chinhda Sharif, Sven Klimpel, Sven Klimpel, Sven Klimpel, Timothy P. Stinear, Luciano A. Moreira, Nicholas J. Tobias, Nicholas J. Tobias, Marcelo G. Lorenzo
Published 2021-08-01

Serological evaluation of Mycobacterium ulcerans antigens identified by comparative genomics.

by Sacha J Pidot, Jessica L Porter, Laurent Marsollier, Annick Chauty, Florence Migot-Nabias, Cyril Badaut, Angèle Bénard, Marie-Therese Ruf, Torsten Seemann, Paul D R Johnson, John K Davies, Grant A Jenkin, Gerd Pluschke, Timothy P Stinear
Published 2010-01-01

A major role for mammals in the ecology of Mycobacterium ulcerans.

by Janet A M Fyfe, Caroline J Lavender, Kathrine A Handasyde, Alistair R Legione, Carolyn R O'Brien, Timothy P Stinear, Sacha J Pidot, Torsten Seemann, M Eric Benbow, John R Wallace, Christina McCowan, Paul D R Johnson
Published 2010-08-01

Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)

by Romain Guérillot, Lucy Li, Sarah Baines, Brian Howden, Mark B. Schultz, Torsten Seemann, Ian Monk, Sacha J. Pidot, Wei Gao, Stefano Giulieri, Anders Gonçalves da Silva, Anthony D’Agata, Takehiro Tomita, Anton Y. Peleg, Timothy P. Stinear, Benjamin P. Howden
Published 2018-08-01

Correction: Mycolactone Gene Expression Is Controlled by Strong SigA-Like Promoters with Utility in Studies of Mycobacterium ulcerans and Buruli Ulcer

by Nicholas J. Tobias, Torsten Seemann, Sacha J. Pidot, Jessica L. Porter, Laurent Marsollier, Estelle Marion, Franck Letournel, Tasnim Zakir, Joseph Azuolas, John R. Wallace, Hui Hong, John K. Davies, Benjamin P. Howden, Paul D. R. Johnson, Grant A. Jenkin, Timothy P. Stinear
Published 2010-02-01

Correction: Mycolactone Gene Expression Is Controlled by Strong SigA-Like Promoters with Utility in Studies of and Buruli Ulcer.

by Nicholas J. Tobias, Torsten Seemann, Sacha J. Pidot, Jessica L. Porter, Laurent Marsollier, Estelle Marion, Franck Letournel, Tasnim Zakir, Joseph Azuolas, John R. Wallace, Hui Hong, John K. Davies, Benjamin P. Howden, Paul D. R. Johnson, Grant A. Jenkin, Timothy P. Stinear
Published 2010-02-01

Mycolactone gene expression is controlled by strong SigA-like promoters with utility in studies of Mycobacterium ulcerans and buruli ulcer.

by Nicholas J Tobias, Torsten Seemann, Sacha J Pidot, Jessica L Porter, Laurent Marsollier, Estelle Marion, Franck Letournel, Tasnim Zakir, Joseph Azuolas, John R Wallace, Hui Hong, John K Davies, Benjamin P Howden, Paul D R Johnson, Grant A Jenkin, Timothy P Stinear
Published 2009-01-01

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering.

by Brendon M Lee, Liam K Harold, Deepak V Almeida, Livnat Afriat-Jurnou, Htin Lin Aung, Brian M Forde, Kiel Hards, Sacha J Pidot, F Hafna Ahmed, A Elaaf Mohamed, Matthew C Taylor, Nicholas P West, Timothy P Stinear, Chris Greening, Scott A Beatson, Eric L Nuermberger, Gregory M Cook, Colin J Jackson
Published 2020-02-01

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

by Ian R. Monk, Nausad Shaikh, Stephanie L. Begg, Mike Gajdiss, Liam K. R. Sharkey, Jean Y. H. Lee, Sacha J. Pidot, Torsten Seemann, Michael Kuiper, Brit Winnen, Rikki Hvorup, Brett M. Collins, Gabriele Bierbaum, Saumya R. Udagedara, Jacqueline R. Morey, Neha Pulyani, Benjamin P. Howden, Megan J. Maher, Christopher A. McDevitt, Glenn F. King, Timothy P. Stinear
Published 2019-07-01