Antipsychotic Treatment of Behavioral and Psychological Symptoms of Dementia (BPSD): Management of Extrapyramidal Side Effects

by Yukihiro Ohno, Naofumi Kunisawa, Saki Shimizu
Published 2019-09-01

Inwardly Rectifying Potassium Channel Kir4.1 as a Novel Modulator of BDNF Expression in Astrocytes

by Yukihiro Ohno, Masato Kinboshi, Saki Shimizu
Published 2018-10-01

Effects of Tandospirone, a 5-HT1A Agonistic Anxiolytic Agent, on Haloperidol-Induced Catalepsy and Forebrain Fos Expression in Mice

by Yukihiro Ohno, Saki Shimizu, Junta Imaki
Published 2009-01-01

Interaction between anti-Alzheimer and antipsychotic drugs in modulating extrapyramidal motor disorders in mice

by Saki Shimizu, Yuto Mizuguchi, Akira Sobue, Mai Fujiwara, Tomoki Morimoto, Yukihiro Ohno
Published 2015-04-01

Serotonergic modulation of nicotine-induced kinetic tremor in mice

by Naofumi Kunisawa, Higor A. Iha, Yuji Nomura, Misaki Onishi, Nami Matsubara, Saki Shimizu, Yukihiro Ohno
Published 2017-06-01

Glycine-Binding Site Stimulants of NMDA Receptors Alleviate Extrapyramidal Motor Disorders by Activating the Nigrostriatal Dopaminergic Pathway

by Saki Shimizu, Shunsaku Sogabe, Ryoto Yanagisako, Akiyoshi Inada, Megumi Yamanaka, Higor A. Iha, Yukihiro Ohno
Published 2017-07-01

Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in <i>Leucine-Rich Glioma-Inactivated 1</i> (<i>Lgi1</i>) Mutant Rats

by Masato Kinboshi, Saki Shimizu, Tomoji Mashimo, Tadao Serikawa, Hidefumi Ito, Akio Ikeda, Ryosuke Takahashi, Yukihiro Ohno
Published 2019-02-01

Hcn1 is a tremorgenic genetic component in a rat model of essential tremor.

by Yukihiro Ohno, Saki Shimizu, Ayaka Tatara, Takuji Imaoku, Takahiro Ishii, Masashi Sasa, Tadao Serikawa, Takashi Kuramoto
Published 2015-01-01

Scn1a missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures

by Yukihiro Ohno, Shizuka Ishihara, Tomoji Mashimo, Nobumasa Sofue, Saki Shimizu, Takuji Imaoku, Toshiko Tsurumi, Masashi Sasa, Tadao Serikawa
Published 2011-02-01

A missense mutation of the gene encoding synaptic vesicle glycoprotein 2A (SV2A) confers seizure susceptibility by disrupting amygdalar synaptic GABA release

by Kentaro Tokudome, Takahiro Okumura, Ryo Terada, Saki Shimizu, Naofumi Kunisawa, Tomoji Mashimo, Tomoji Mashimo, Tadao Serikawa, Tadao Serikawa, Masashi Sasa, Yukihiro Ohno
Published 2016-07-01

Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents

by Naofumi Kunisawa, Saki Shimizu, Masaki Kato, Higor A. Iha, Chihiro Iwai, Mai Hashimura, Mizuki Ogawa, Shohei Kawaji, Kazuma Kawakita, Keisuke Abe, Yukihiro Ohno
Published 2018-06-01

RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice

by Saki Shimizu, Gene-Errol Ringpis, Matthew D Marsden, Ruth V Cortado, Holly M Wilhalme, David Elashoff, Jerome A Zack, Irvin S Y Chen, Dong Sung An
Published 2015-01-01

Antiepileptic Drugs Elevate Astrocytic Kir4.1 Expression in the Rat Limbic Region

by Takahiro Mukai, Masato Kinboshi, Masato Kinboshi, Masato Kinboshi, Yuki Nagao, Saki Shimizu, Asuka Ono, Yoshihisa Sakagami, Aoi Okuda, Megumi Fujimoto, Hidefumi Ito, Akio Ikeda, Yukihiro Ohno
Published 2018-08-01

Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1

by Wannisa Khamaikawin, Saki Shimizu, Masakazu Kamata, Ruth Cortado, Yujin Jung, Jennifer Lam, Jing Wen, Patrick Kim, Yiming Xie, Sanggu Kim, Hubert Arokium, Angela P. Presson, Irvin S.Y. Chen, Dong Sung An
Published 2018-06-01

Longitudinal clonal tracking in humanized mice reveals sustained polyclonal repopulation of gene-modified human-HSPC despite vector integration bias

by Gajendra W. Suryawanshi, Hubert Arokium, Sanggu Kim, Wannisa Khamaikawin, Samantha Lin, Saki Shimizu, Koollawat Chupradit, YooJin Lee, Yiming Xie, Xin Guan, Vasantika Suryawanshi, Angela P. Presson, Dong-Sung An, Irvin S. Y. Chen
Published 2021-10-01

Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes

by Masato Kinboshi, Masato Kinboshi, Masato Kinboshi, Takahiro Mukai, Yuki Nagao, Yusuke Matsuba, Yoshimi Tsuji, Shiho Tanaka, Kentaro Tokudome, Kentaro Tokudome, Saki Shimizu, Hidefumi Ito, Akio Ikeda, Atsushi Inanobe, Yoshihisa Kurachi, Seiji Inoue, Yukihiro Ohno
Published 2017-12-01

Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice.

by Gene-Errol E Ringpis, Saki Shimizu, Hubert Arokium, Joanna Camba-Colón, Maria V Carroll, Ruth Cortado, Yiming Xie, Patrick Y Kim, Anna Sahakyan, Emily L Lowe, Munetoshi Narukawa, Fadi N Kandarian, Bryan P Burke, Geoff P Symonds, Dong Sung An, Irvin S Y Chen, Masakazu Kamata
Published 2012-01-01

Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector

by Bryan P Burke, Bernard R Levin, Jane Zhang, Anna Sahakyan, Joshua Boyer, Maria V Carroll, Joanna Camba Colón, Naomi Keech, Valerie Rezek, Gregory Bristol, Erica Eggers, Ruth Cortado, Maureen P Boyd, Helen Impey, Saki Shimizu, Emily L Lowe, Gene-Errol E Ringpis, Sohn G Kim, Dimitrios N Vatakis, Louis R Breton, Jeffrey S Bartlett, Irvin S Y Chen, Scott G Kitchen, Dong Sung An, Geoff P Symonds
Published 2015-01-01