Cardiac myosin binding protein C phosphorylation affects cross-bridge cycle's elementary steps in a site-specific manner.

by Li Wang, Sakthivel Sadayappan, Masakata Kawai
Published 2014-01-01

Distal Arthrogryposis and Lethal Congenital Contracture Syndrome – An Overview

by Darshini Desai, Danielle Stiene, Taejeong Song, Sakthivel Sadayappan
Published 2020-06-01

Monoclonal Antibody-Based Immunotherapy and Its Role in the Development of Cardiac Toxicity

by Mohit Kumar, Chellappagounder Thangavel, Richard C. Becker, Sakthivel Sadayappan
Published 2021-12-01

Targeted genome-wide enrichment of functional regions.

by Periannan Senapathy, Ashwini Bhasi, Jeffrey Mattox, Perundurai S Dhandapany, Sakthivel Sadayappan
Published 2010-06-01

Recent Advances in the Molecular Genetics of Familial Hypertrophic Cardiomyopathy in South Asian Descendants

by Jessica Kraker, Shivkumar Viswanathan, Ralph Knöll, Ralph Knöll, Sakthivel Sadayappan
Published 2016-10-01

A Novel Homozygous Intronic Variant in TNNT2 Associates With Feline Cardiomyopathy

by James W. McNamara, Maggie Schuckman, Richard C. Becker, Sakthivel Sadayappan
Published 2020-11-01

Genetic Modifiers of Hereditary Neuromuscular Disorders and Cardiomyopathy

by Sholeh Bazrafshan, Hani Kushlaf, Mashhood Kakroo, John Quinlan, Richard C. Becker, Sakthivel Sadayappan
Published 2021-02-01

Upregulated Angiogenesis Is Incompetent to Rescue Dilated Cardiomyopathy Phenotype in Mice

by Mohammed Arif, Perwez Alam, Rafeeq PH Ahmed, Raghav Pandey, Hafeez M Faridi, Sakthivel Sadayappan
Published 2021-03-01

KLF2 in Myeloid Lineage Cells Regulates the Innate Immune Response during Skeletal Muscle Injury and Regeneration

by Palanikumar Manoharan, Taejeong Song, Tatiana L. Radzyukevich, Sakthivel Sadayappan, Jerry B Lingrel, Judith A. Heiny
Published 2019-07-01

Calcium-Dependent Interaction Occurs between Slow Skeletal Myosin Binding Protein C and Calmodulin

by Tzvia I. Springer, Christian W. Johns, Jana Cable, Brian Leei Lin, Sakthivel Sadayappan, Natosha L. Finley
Published 2017-12-01

Dilated cardiomyopathy-mediated heart failure induces a unique skeletal muscle myopathy with inflammation

by Taejeong Song, Palanikumar Manoharan, Douglas P. Millay, Sheryl E. Koch, Jack Rubinstein, Judith A. Heiny, Sakthivel Sadayappan
Published 2019-01-01

Hypertrophic cardiomyopathy clinical phenotype is independent of gene mutation and mutation dosage.

by Shiv Kumar Viswanathan, Heather K Sanders, James W McNamara, Aravindakshan Jagadeesan, Arshad Jahangir, A Jamil Tajik, Sakthivel Sadayappan
Published 2017-01-01

Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle

by Qingnian Goh, Taejeong Song, Michael J Petrany, Alyssa AW Cramer, Chengyi Sun, Sakthivel Sadayappan, Se-Jin Lee, Douglas P Millay
Published 2019-04-01

Cardiac myosin binding protein-C plays no regulatory role in skeletal muscle structure and function.

by Brian Lin, Suresh Govindan, Kyounghwan Lee, Piming Zhao, Renzhi Han, K Elisabeth Runte, Roger Craig, Bradley M Palmer, Sakthivel Sadayappan
Published 2013-01-01

The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling

by Athiththan Yogeswaran, Christian Troidl, James W. McNamara, Jochen Wilhelm, Theresa Truschel, Laila Widmann, Muhammad Aslam, Christian W. Hamm, Sakthivel Sadayappan, Christoph Lipps
Published 2021-05-01

Enhanced cardiac function in Gravin mutant mice involves alterations in the β-adrenergic receptor signaling cascade.

by Ashley N Guillory, Xing Yin, Cori S Wijaya, Andrea C Diaz Diaz, Abeer Rababa'h, Sonal Singh, Fatin Atrooz, Sakthivel Sadayappan, Bradley K McConnell
Published 2013-01-01

Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains

by Alyssa A. W. Cramer, Vikram Prasad, Einar Eftestøl, Taejeong Song, Kenth-Arne Hansson, Hannah F. Dugdale, Sakthivel Sadayappan, Julien Ochala, Kristian Gundersen, Douglas P. Millay
Published 2020-12-01

Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation

by Thomas L. Lynch, Mayandi Sivaguru, Murugesan Velayutham, Arturo J. Cardounel, Michelle Michels, David Barefield, Suresh Govindan, Cristobal dos Remedios, Jolanda van der Velden, Sakthivel Sadayappan
Published 2015-01-01

Sham surgery and inter-individual heterogeneity are major determinants of monocyte subset kinetics in a mouse model of myocardial infarction.

by Jedrzej Hoffmann, Manuel Ospelt, Christian Troidl, Sandra Voss, Christoph Liebetrau, Won-Keun Kim, Andreas Rolf, Astrid Wietelmann, Thomas Braun, Kerstin Troidl, Sakthivel Sadayappan, David Barefield, Christian Hamm, Holger Nef, Helge Möllmann
Published 2014-01-01

Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

by Wei Huang, Yuliang Feng, Jialiang Liang, Hao Yu, Cheng Wang, Boyu Wang, Mingyang Wang, Lin Jiang, Wei Meng, Wenfeng Cai, Mario Medvedovic, Jenny Chen, Christian Paul, W. Sean Davidson, Sakthivel Sadayappan, Peter J. Stambrook, Xi-Yong Yu, Yigang Wang
Published 2018-02-01