Direct repair of 3,N[superscript 4]-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase

by Fu, Dragony, Samson, Leona D
Published 2015

Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB)

by Van Loon, Barbara, Samson, Leona D
Published 2015

Balancing repair and tolerance of DNA damage caused by alkylating agents

by Fu, Dragony, Calvo, Jennifer A., Samson, Leona D
Published 2014

The human gut bacterial genotoxin colibactin alkylates DNA

by Ngo, Lizzie, Samson, Leona D., Engelward, Bevin P.
Published 2020

A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects

by Valiathan, Chandni, McFaline, Jose Luis, Samson, Leona D.
Published 2015

Inter-individual variation in DNA repair capacity: A need for multi-pathway functional assays to promote translational DNA repair research

by Nagel, Zachary D., Chaim, Isaac Alexander, Samson, Leona D
Published 2015

Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins

by Bugni, J. M., Meira, Lisiane B., Samson, Leona D.
Published 2014

Cell-cycle-dependent transcriptional and translational DNA-damage response of 2 ribonucleotide reductase genes in S. cerevisiae

by Mazumder, Aprotim, Tummler, Katja, Bathe, Mark, Samson, Leona D
Published 2013

The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants

by Hübscher, Ullrich, Fu, Dragony, Samson, Leona D, Van Loon, Barbara
Published 2017

Inflammation-induced DNA damage, mutations and cancer

by Kay, Jennifer Elizabeth, Thadhani, Elina, Samson, Leona D, Engelward, Bevin P
Published 2020

The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury

by Yu, Amy Marie, Calvo, Jennifer A., Muthupalani, Sureshkumar, Samson, Leona D
Published 2016

Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation

by Ngo, Le P, Ge, Jing, Samson, Leona D, Engelward, Bevin P
Published 2020

Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response

by Beharry, Andrew A., Kool, Eric T., Samson, Leona D, Nagel, Zachary D.
Published 2017

PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration

by Allocca, Mariacarmela, Corrigan, Joshua, Fake, Kimberly, Samson, Leona D, Calvo, Jennifer A.
Published 2018

Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms

by Margulies, Carrie Marie, Chaim, Isaac Alexander, Mazumder, Aprotim, Criscione, June, Samson, Leona D
Published 2018

Both base excision repair and O-6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis

by Samson, Leona D., Wirtz, Stefan, Nagel, Georg, Eshkind, Leonid, Neurath, Markus F., Kaina, Bernd
Published 2011

O[superscript 6]-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation

by Noonan, Ericka M., Shah, Dharini, Yaffe, Michael B, Lauffenburger, Douglas A, Samson, Leona D
Published 2014

Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae

by Mazumder, Aprotim, Bathe, Mark, Samson, Leona D., Pesudo Quiros, Laia, McRee, Siobhan K.
Published 2013

Microfluidic genome-wide profiling of intrinsic electrical properties in Saccharomyces cerevisiae

by Vahey, Michael D., Quiros Pesudo, Laia, Svensson, J. Peter, Voldman, Joel, Samson, Leona D
Published 2014

Identification of Novel Human Damage Response Proteins Targeted through Yeast Orthology

by Svensson, J. Peter, Fry, Rebecca C., Wang, Emma, Somoza, Luis A., Samson, Leona D.
Published 2012