Structural binding site comparisons reveal Crizotinib as a novel LRRK2 inhibitor

by Sarah Naomi Bolz, Sebastian Salentin, Gary Jennings, V. Joachim Haupt, Jared Sterneckert, Michael Schroeder
Published 2021-01-01

Drug repositioning or target repositioning: A structural perspective of drug-target-indication relationship for available repurposed drugs

by Daniele Parisi, Melissa F. Adasme, Anastasia Sveshnikova, Sarah Naomi Bolz, Yves Moreau, Michael Schroeder
Published 2020-01-01

Deep Learning Improves Pancreatic Cancer Diagnosis Using RNA-Based Variants

by Ali Al-Fatlawi, Negin Malekian, Sebastián García, Andreas Henschel, Ilwook Kim, Andreas Dahl, Beatrix Jahnke, Peter Bailey, Sarah Naomi Bolz, Anna R. Poetsch, Sandra Mahler, Robert Grützmann, Christian Pilarsky, Michael Schroeder
Published 2021-05-01

Repositioned Drugs for Chagas Disease Unveiled via Structure-Based Drug Repositioning

by Melissa F. Adasme, Sarah Naomi Bolz, Lauren Adelmann, Sebastian Salentin, V. Joachim Haupt, Adriana Moreno-Rodríguez, Benjamín Nogueda-Torres, Verónica Castillo-Campos, Lilián Yepez-Mulia, José A. De Fuentes-Vicente, Gildardo Rivera, Michael Schroeder
Published 2020-11-01