Substrate delivery by the AAA+ ClpX and ClpC1 unfoldases activates the mycobacterial ClpP1P2 peptidase

by Schmitz, Karl Robert, Sauer, Robert T.
Published 2017

Subunit asymmetry and roles of conformational switching in the hexameric AAA+ ring of ClpX

by Stinson, Benjamin Michael, Baytshtok, Vladimir, Schmitz, Karl Robert, Baker, Tania, Sauer, Robert T.
Published 2017

Examination of a Structural Model of Peptidomimicry by Cyclic Acyldepsipeptide Antibiotics in Their Interaction with the ClpP Peptidase

by Carney, Daniel W., Scruse, Anthony C., Sello, Jason K., Schmitz, Karl Robert, Sauer, Robert T.
Published 2017

A Simple Fragment of Cyclic Acyldepsipeptides Is Necessary and Sufficient for ClpP Activation and Antibacterial Activity

by Carney, Daniel W., Compton, Corey L., Stevens, Julia P., Sello, Jason K., Schmitz, Karl Robert, Sauer, Robert T.
Published 2017

Stochastic but Highly Coordinated Protein Unfolding and Translocation by the ClpXP Proteolytic Machine

by Cordova, Juan Carlos, Aubin-Tam, Lang, Matthew J, Olivares, Adrian O., Shin, Yongdae, Calmat, Stephane Geraldine Michele, Schmitz, Karl Robert, Baker, Tania, Sauer, Robert T., Stinson, Benjamin Michael
Published 2017

Highly Dynamic Interactions Maintain Kinetic Stability of the ClpXP Protease During the ATP-Fueled Mechanical Cycle

by Sello, Jason K., Sauer, Robert T., Amor, Alvaro Jorge, Baker, Tania, Schmitz, Karl R.
Published 2017