Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.

by Udita Upadhyay, Gerald Z Zhuang, Luda Diatchenko, Marc Parisien, Yuan Kang, Konstantinos D Sarantopoulos, Eden R Martin, Shad B Smith, William Maixner, Roy C Levitt
Published 2019-06-01

Effect of Human Genetic Variability on Gene Expression in Dorsal Root Ganglia and Association with Pain Phenotypes

by Marc Parisien, Samar Khoury, Anne-Julie Chabot-Doré, Susana G. Sotocinal, Gary D. Slade, Shad B. Smith, Roger B. Fillingim, Richard Ohrbach, Joel D. Greenspan, William Maixner, Jeffrey S. Mogil, Inna Belfer, Luda Diatchenko
Published 2017-05-01

Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.

by Gerald Z Zhuang, Benjamin Keeler, Jeff Grant, Laura Bianchi, Eugene S Fu, Yan Ping Zhang, Diana M Erasso, Jian-Guo Cui, Tim Wiltshire, Qiongzhen Li, Shuanglin Hao, Konstantinos D Sarantopoulos, Keith Candiotti, Sarah M Wishnek, Shad B Smith, William Maixner, Luda Diatchenko, Eden R Martin, Roy C Levitt
Published 2015-01-01