The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells

by Zulema Romero, Beatriz Campo-Fernandez, Jennifer Wherley, Michael L Kaufman, Fabrizia Urbinati, Aaron R Cooper, Megan D Hoban, Kismet M Baldwin, Dianne Lumaquin, Xiaoyan Wang, Shantha Senadheera, Roger P Hollis, Donald B Kohn
Published 2015-01-01

Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences

by Richard A. Morgan, Feiyang Ma, Mildred J. Unti, Devin Brown, Paul George Ayoub, Curtis Tam, Lindsay Lathrop, Bamidele Aleshe, Ryo Kurita, Yukio Nakamura, Shantha Senadheera, Ryan L. Wong, Roger P. Hollis, Matteo Pellegrini, Donald B. Kohn
Published 2020-06-01

Global and Local Manipulation of DNA Repair Mechanisms to Alter Site-Specific Gene Editing Outcomes in Hematopoietic Stem Cells

by Elizabeth K. Benitez, Anastasia Lomova Kaufman, Lilibeth Cervantes, Danielle N. Clark, Paul G. Ayoub, Shantha Senadheera, Kyle Osborne, Julie M. Sanchez, Ralph Valentine Crisostomo, Xiaoyan Wang, Nina Reuven, Yosef Shaul, Roger P. Hollis, Zulema Romero, Donald B. Kohn
Published 2020-12-01