Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype

by Chris Rudyk, Zach Dwyer, Shawn Hayley, CLINT membership
Published 2019-06-01

Stressor-like effects of c-Jun N-terminal kinase (JNK) inhibition.

by Melanie Clarke, Rowan Pentz, Jessica Bobyn, Shawn Hayley
Published 2012-01-01

Major Alterations of Phosphatidylcholine and Lysophosphotidylcholine Lipids in the Substantia Nigra Using an Early Stage Model of Parkinson’s Disease

by Kyle Farmer, Catherine A. Smith, Shawn Hayley, Jeffrey Smith
Published 2015-08-01

Proinflammatory cytokines differentially influence adult hippocampal cell proliferation depending upon the route and chronicity of administration

by Julie Anne Seguin, Jordan Brennan, Emily Mangano, Shawn Hayley
Published 2008-12-01

Paraquat and psychological stressor interactions as pertains to Parkinsonian co-morbidity

by Chris Rudyk, Darcy Litteljohn, Shuaib Syed, Zach Dwyer, Shawn Hayley
Published 2015-01-01

Inflammatory Mechanisms of Neurodegeneration in Toxin-Based Models of Parkinson's Disease

by Darcy Litteljohn, Emily Mangano, Melanie Clarke, Jessica Bobyn, Kerry Moloney, Shawn Hayley
Published 2011-01-01

Perinatal antibiotic exposure alters composition of murine gut microbiota and may influence later responses to peanut antigen

by Rozlyn C. T. Boutin, Zach Dwyer, Kyle Farmer, Chris Rudyk, Mark R. Forbes, Shawn Hayley
Published 2018-11-01

Antidepressant-like effects of erythropoietin: a focus on behavioural and hippocampal processes.

by Meagan Osborn, Nazneen Rustom, Melanie Clarke, Darcy Litteljohn, Chris Rudyk, Hymie Anisman, Shawn Hayley
Published 2013-01-01

Chronic unpredictable stress influenced the behavioral but not the neurodegenerative impact of paraquat

by Chris Rudyk, Zach Dwyer, Jessica McNeill, Natalina Salmaso, Kyle Farmer, Natalie Prowse, Shawn Hayley
Published 2019-11-01

Age and Chronicity of Administration Dramatically Influenced the Impact of Low Dose Paraquat Exposure on Behavior and Hypothalamic-Pituitary-Adrenal Activity

by Chris A. Rudyk, Jessica McNeill, Natalie Prowse, Zach Dwyer, Kyle Farmer, Darcy Litteljohn, Warren Caldwell, Shawn Hayley
Published 2017-07-01

The Role of the Val66Met Polymorphism of the Brain Derived Neurotrophic Factor Gene in Coping Strategies Relevant to Depressive Symptoms.

by Warren Caldwell, Opal A McInnis, Robyn J McQuaid, Gele Liu, John D Stead, Hymie Anisman, Shawn Hayley
Published 2013-01-01

Microglia depletion prior to lipopolysaccharide and paraquat treatment differentially modulates behavioral and neuronal outcomes in wild type and G2019S LRRK2 knock-in mice

by Zach Dwyer, Chris Rudyk, Divya Situt, Sheryl Beauchamp, Jawaria Abdali, Anu Dinesh, Nathalie Legancher, Hongyu Sun, Michael Schlossmacher, Shawn Hayley
Published 2020-05-01

Alleviating toxic α-Synuclein accumulation by membrane depolarization: evidence from an in vitro model of Parkinson’s disease

by Alysia Ross, Viktoria Xing, Ting Ting Wang, Samantha C. Bureau, Giovana A. Link, Teresa Fortin, Hui Zhang, Shawn Hayley, Hongyu Sun
Published 2020-07-01

The impact of dextran sodium sulphate and probiotic pre-treatment in a murine model of Parkinson’s disease

by Zach Dwyer, Melany Chaiquin, Jeffrey Landrigan, Kiara Ayoub, Pragya Shail, Julianna Rocha, Christie L. Childers, Kenneth B. Storey, Dana J. Philpott, Hongyu Sun, Shawn Hayley
Published 2021-01-01