Role of DNA repair defects in predicting immunotherapy response

by Jing Zhang, David J. H. Shih, Shiaw-Yih Lin
Published 2020-06-01

Mechanisms of immunogenic cell death and immune checkpoint blockade therapy

by Richard A. Lin, Jessica K. Lin, Shiaw‐Yih Lin
Published 2021-06-01

Connecting the Dots: From DNA Damage and Repair to Aging

by Mei-Ren Pan, Kaiyi Li, Shiaw-Yih Lin, Wen-Chun Hung
Published 2016-05-01

siRNA-based targeting of cyclin E overexpression inhibits breast cancer cell growth and suppresses tumor development in breast cancer mouse model.

by Yulong Liang, Hong Gao, Shiaw-Yih Lin, John A Goss, Francis C Brunicardi, Kaiyi Li
Published 2010-01-01

Genomic-Glycosylation Aberrations in Tumor Initiation, Progression and Management

by Carman K.M. Ip, Jun Yin, Patrick K.S. Ng, Shiaw-Yih Lin, Gordon B. Mills
Published 2016-12-01

MicroPET/CT Imaging of AXL Downregulation by HSP90 Inhibition in Triple-Negative Breast Cancer

by Wanqin Wang, Jun Zhao, Xiaoxia Wen, Curtis Chun-Jen Lin, Junjie Li, Qian Huang, Yongqiang Yu, Shiaw-Yih Lin, Chun Li
Published 2017-01-01

A Gene Expression Signature to Predict Nucleotide Excision Repair Defects and Novel Therapeutic Approaches

by Rongbin Wei, Hui Dai, Jing Zhang, David J. H. Shih, Yulong Liang, Pengfeng Xiao, Daniel J. McGrail, Shiaw-Yih Lin
Published 2021-05-01

Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers

by Daniel J. McGrail, Lorenzo Federico, Yongsheng Li, Hui Dai, Yiling Lu, Gordon B. Mills, Song Yi, Shiaw-Yih Lin, Nidhi Sahni
Published 2018-04-01

BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice.

by Yulong Liang, Hong Gao, Shiaw-Yih Lin, Guang Peng, Xingxu Huang, Pumin Zhang, John A Goss, Francis C Brunicardi, Asha S Multani, Sandy Chang, Kaiyi Li
Published 2010-01-01

Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

by Daniel J. McGrail, Curtis Chun-Jen Lin, Jeannine Garnett, Qingxin Liu, Wei Mo, Hui Dai, Yiling Lu, Qinghua Yu, Zhenlin Ju, Jun Yin, Christopher P. Vellano, Bryan Hennessy, Gordon B. Mills, Shiaw-Yih Lin
Published 2017-03-01

Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer

by Yongsheng Li, Nidhi Sahni, Rita Pancsa, Daniel J. McGrail, Juan Xu, Xu Hua, Jasmin Coulombe-Huntington, Michael Ryan, Boranai Tychhon, Dhanistha Sudhakar, Limei Hu, Michael Tyers, Xiaoqian Jiang, Shiaw-Yih Lin, M. Madan Babu, Song Yi
Published 2017-10-01

PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma

by Xian-De Liu, Wen Kong, Christine B. Peterson, Daniel J. McGrail, Anh Hoang, Xuesong Zhang, Truong Lam, Patrick G. Pilie, Haifeng Zhu, Kathryn E. Beckermann, Scott M. Haake, Sevinj Isgandrova, Margarita Martinez-Moczygemba, Nidhi Sahni, Nizar M. Tannir, Shiaw-Yih Lin, W. Kimryn Rathmell, Eric Jonasch
Published 2020-05-01