Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168

by Tomio S. Takahashi, Yoshihiro Hirade, Aya Toma, Yusuke Sato, Atsushi Yamagata, Sakurako Goto-Ito, Akiko Tomita, Shinichiro Nakada, Shuya Fukai
Published 2018-01-01

Structural basis for ubiquitin recognition by ubiquitin-binding zinc finger of FAAP20.

by Aya Toma, Tomio S Takahashi, Yusuke Sato, Atsushi Yamagata, Sakurako Goto-Ito, Shinichiro Nakada, Atsuhiko Fukuto, Yasunori Horikoshi, Satoshi Tashiro, Shuya Fukai
Published 2015-01-01

UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks

by Remi Akagawa, Hai Thanh Trinh, Liton Kumar Saha, Masataka Tsuda, Kouji Hirota, Shintaro Yamada, Atsushi Shibata, Masato T. Kanemaki, Shinichiro Nakada, Shunichi Takeda, Hiroyuki Sasanuma
Published 2020-04-01

A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions.

by Pamela Kanellis, Mark Gagliardi, Judit P Banath, Rachel K Szilard, Shinichiro Nakada, Sarah Galicia, Frederic D Sweeney, Diane C Cabelof, Peggy L Olive, Daniel Durocher
Published 2007-08-01

BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation

by Mayu Isono, Atsuko Niimi, Takahiro Oike, Yoshihiko Hagiwara, Hiro Sato, Ryota Sekine, Yukari Yoshida, Shin-Ya Isobe, Chikashi Obuse, Ryotaro Nishi, Elena Petricci, Shinichiro Nakada, Takashi Nakano, Atsushi Shibata
Published 2017-01-01

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

by Hiroyuki Morisaka, Kazuto Yoshimi, Yuya Okuzaki, Peter Gee, Yayoi Kunihiro, Ekasit Sonpho, Huaigeng Xu, Noriko Sasakawa, Yuki Naito, Shinichiro Nakada, Takashi Yamamoto, Shigetoshi Sano, Akitsu Hotta, Junji Takeda, Tomoji Mashimo
Published 2019-12-01