The gut–brain axis: Identifying new therapeutic approaches for type 2 diabetes, obesity, and related disorders

by Paul Richards, Nancy A. Thornberry, Shirly Pinto
Published 2021-04-01

Identification and characterization of a novel DGAT1 missense mutation associated with congenital diarrhea[S]

by Nina L. Gluchowski, Chandramohan Chitraju, Joseph A. Picoraro, Niklas Mejhert, Shirly Pinto, Winnie Xin, Daniel S. Kamin, Harland S. Winter, Wendy K. Chung, Tobias C. Walther, Robert V. Farese, Jr.
Published 2017-06-01

Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors.

by Eric S Muise, Yonghua Zhu, Andreas Verras, Bindhu V Karanam, Judith Gorski, Drew Weingarth, Hua V Lin, Joyce Hwa, John R Thompson, Guanghui Hu, Jian Liu, Shuwen He, Robert J DeVita, Dong-Ming Shen, Shirly Pinto
Published 2014-01-01

Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]

by Seongah Han, Taro E. Akiyama, Stephen F. Previs, Kithsiri Herath, Thomas P. Roddy, Kristian K. Jensen, Hong-Ping Guan, Beth A. Murphy, Lesley A. McNamara, Xun Shen, Walter Strapps, Brian K. Hubbard, Shirly Pinto, Cai Li, Jing Li
Published 2013-10-01

Diacylglycerol acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release.

by Hua V Lin, Dunlu Chen, Zhu Shen, Lei Zhu, Xuesong Ouyang, Aurawan Vongs, Yanqing Kan, John M Levorse, Edward J Kowalik, Daphne M Szeto, Xiaorui Yao, Jianying Xiao, Shirley Chen, Jinqi Liu, Marga Garcia-Calvo, Myung K Shin, Shirly Pinto
Published 2013-01-01

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S]

by Kristian K. Jensen, Marija Tadin-Strapps, Sheng-ping Wang, James Hubert, Yanqing Kan, Yong Ma, David G. McLaren, Stephen F. Previs, Kithsiri B. Herath, Ablatt Mahsut, Andy Liaw, Shubing Wang, Steven J. Stout, CarolAnn Keohan, Gail Forrest, David Coelho, Satya Yendluri, Stephanie Williams, Martin Koser, Steven Bartz, Karen O. Akinsanya, Shirly Pinto
Published 2016-12-01

The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species

by David G. McLaren, Timothy He, Sheng-Ping Wang, Vivienne Mendoza, Raymond Rosa, Karen Gagen, Gowri Bhat, Kithsiri Herath, Paul L. Miller, Sloan Stribling, Andrew Taggart, Jason Imbriglio, Jinqi Liu, Dunlu Chen, Shirly Pinto, James M. Balkovec, Robert J. DeVita, Donald J. Marsh, Jose M. Castro-Perez, Alison Strack, Douglas G. Johns, Stephen F. Previs, Brian K. Hubbard, Thomas P. Roddy
Published 2011-06-01

Discovery of a new class of integrin antibodies for fibrosis

by Ji Zhang, Tao Wang, Ashmita Saigal, Josephine Johnson, Jennifer Morrisson, Sahba Tabrizifard, Scott A. Hollingsworth, Michael J. Eddins, Wenxian Mao, Kim O’Neill, Margarita Garcia-Calvo, Ester Carballo-Jane, DingGang Liu, Taewon Ham, Qiong Zhou, Weifeng Dong, Hsien-Wei Meng, Jacqueline Hicks, Tian-Quan Cai, Taro Akiyama, Shirly Pinto, Alan C. Cheng, Thomas Greshock, John C. Marquis, Zhao Ren, Saswata Talukdar, Hussam Hisham Shaheen, Masahisa Handa
Published 2021-01-01

Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis

by Ji Zhang, Eric S. Muise, Seongah Han, Peter S. Kutchukian, Philippe Costet, Yonghua Zhu, Yanqing Kan, Haihong Zhou, Vinit Shah, Yongcheng Huang, Ashmita Saigal, Taro E. Akiyama, Xiao-Lan Shen, Tian-Quan Cai, Kashmira Shah, Ester Carballo-Jane, Emanuel Zycband, Lan Yi, Ye Tian, Ying Chen, Jason Imbriglio, Elizabeth Smith, Kristine Devito, James Conway, Li-Jun Ma, Maarten Hoek, Iyassu K. Sebhat, Andrea M. Peier, Saswata Talukdar, David G. McLaren, Stephen F. Previs, Kristian K. Jensen, Shirly Pinto
Published 2020-07-01