Nicotine Effects and the Endogenous Opioid System

by Shiroh Kishioka, Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika
Published 2014-01-01

Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice

by Fumihiro Saika, Shinsuke Matsuzaki, Shiroh Kishioka, Norikazu Kiguchi
Published 2021-04-01

Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain

by Fumihiro Saika, Shinsuke Matsuzaki, Daichi Kobayashi, Daichi Kobayashi, Yuya Ideguchi, Tomoe Y. Nakamura, Shiroh Kishioka, Shiroh Kishioka, Norikazu Kiguchi
Published 2020-06-01

Pharmacological Regulation of Neuropathic Pain Driven by Inflammatory Macrophages

by Norikazu Kiguchi, Daichi Kobayashi, Fumihiro Saika, Shinsuke Matsuzaki, Shiroh Kishioka
Published 2017-11-01

Pioglitazone Attenuates Tactile Allodynia and Thermal Hyperalgesia in Mice Subjected to Peripheral Nerve Injury

by Takehiko Maeda, Norikazu Kiguchi, Yuka Kobayashi, Masanobu Ozaki, Shiroh Kishioka
Published 2008-01-01

HMGB1 as a Potential Therapeutic Target for Neuropathic Pain

by Takehiko Maeda, Masanobu Ozaki, Yuka Kobayashi, Norikazu Kiguchi, Shiroh Kishioka
Published 2013-01-01

Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injury

by Norikazu Kiguchi, Daichi Kobayashi, Fumihiro Saika, Shinsuke Matsuzaki, Shiroh Kishioka
Published 2018-03-01

TC-2559, an α4β2 nicotinic acetylcholine receptor agonist, suppresses the expression of CCL3 and IL-1β through STAT3 inhibition in cultured murine macrophages

by Norikazu Kiguchi, Fumihiro Saika, Yuka Kobayashi, Mei-Chuan Ko, Shiroh Kishioka
Published 2015-06-01

Negative Relationship Between Morphine Analgesia and P-Glycoprotein Expression Levels in the Brain

by Wakako Hamabe, Takehiko Maeda, Norikazu Kiguchi, Chizuko Yamamoto, Shogo Tokuyama, Shiroh Kishioka
Published 2007-01-01

CC-Chemokine Ligand 2 Facilitates Conditioned Place Preference to Methamphetamine Through the Activation of Dopamine Systems

by Naoki Wakida, Norikazu Kiguchi, Fumihiro Saika, Hideki Nishiue, Yuka Kobayashi, Shiroh Kishioka
Published 2014-01-01

Activation of Spinal Cholecystokinin and Neurokinin-1 Receptors Is Associated With the Attenuation of Intrathecal Morphine Analgesia Following Electroacupuncture Stimulation in Rat...

by Yohji Fukazawa, Takehiko Maeda, Norikazu Kiguchi, Kazuo Tohya, Michio Kimura, Shiroh Kishioka
Published 2007-01-01

Role of Pharmacokinetic Effects in the Potentiation of Morphine Analgesia by L-Type Calcium Channel Blockers in Mice

by Norifumi Shimizu, Shiroh Kishioka, Takehiko Maeda, Yohji Fukazawa, Chizuko Yamamoto, Masanobu Ozaki, Hiroyuki Yamamoto
Published 2004-01-01

Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation

by Norikazu Kiguchi, Haruka Sakaguchi, Yui Kadowaki, Fumihiro Saika, Yohji Fukazawa, Shinsuke Matsuzaki, Shiroh Kishioka
Published 2017-01-01

Activation of Spinal Anti-analgesic System Following Electroacupuncture Stimulation in Rats

by Yohji Fukazawa, Takehiko Maeda, Wakako Hamabe, Kazumasa Kumamoto, Yuan Gao, Chizuko Yamamoto, Masanobu Ozaki, Shiroh Kishioka
Published 2005-01-01

Involvement of Peripheral Mechanism in the Verapamil-Induced Potentiation of Morphine Analgesia in Mice

by Norifumi Shimizu, Shiroh Kishioka, Takehiko Maeda, Yohji Fukazawa, Yoshihiro Dake, Chizuko Yamamoto, Masanobu Ozaki, Hiroyuki Yamamoto
Published 2004-01-01

Possible Involvement of Endogenous Opioid System Located Downstream of α7 Nicotinic Acetylcholine Receptor in Mice With Physical Dependence on Nicotine

by Keiko Ueno, Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika, Naoki Wakida, Chizuko Yamamoto, Takehiko Maeda, Masanobu Ozaki, Shiroh Kishioka
Published 2014-01-01

Chemogenetic activation of central gastrin‐releasing peptide‐expressing neurons elicits itch‐related scratching behavior in male and female mice

by Norikazu Kiguchi, Yohji Fukazawa, Ayano Saika, Daisuke Uta, Fumihiro Saika, Tomoe Y. Nakamura, Mei‐Chuan Ko, Shiroh Kishioka
Published 2021-05-01