Improving single-cell cloning workflow for gene editing in human pluripotent stem cells

by Yi-Hsien Chen, Shondra M. Pruett-Miller
Published 2018-08-01

Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels.

by Shondra M Pruett-Miller, David W Reading, Shaina N Porter, Matthew H Porteus
Published 2009-02-01

Positional cloning of quantitative trait nucleotides for blood pressure and cardiac QT-interval by targeted CRISPR/Cas9 editing of a novel long non-coding RNA.

by Xi Cheng, Harshal Waghulde, Blair Mell, Eric E Morgan, Shondra M Pruett-Miller, Bina Joe
Published 2017-08-01

Expanding the Repertoire of Target Sites for Zinc Finger Nuclease-mediated Genome Modification

by Kimberly A Wilson, Abbye E McEwen, Shondra M Pruett-Miller, Jiuli Zhang, Eric J Kildebeck, Matthew H Porteus
Published 2013-01-01

Cleavage activates Dispatched for Sonic Hedgehog ligand release

by Daniel P Stewart, Suresh Marada, William J Bodeen, Ashley Truong, Sadie Miki Sakurada, Tanushree Pandit, Shondra M Pruett-Miller, Stacey K Ogden
Published 2018-01-01

The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth

by Baisakhi Mondal, Hongjian Jin, Satish Kallappagoudar, Yurii Sedkov, Tanner Martinez, Monica F Sentmanat, Greg J Poet, Chunliang Li, Yiping Fan, Shondra M Pruett-Miller, Hans-Martin Herz
Published 2020-04-01

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

by Natalya A Ortolano, Alejandra I Romero-Morales, Megan L Rasmussen, Caroline Bodnya, Leigh A Kline, Piyush Joshi, Jon P Connelly, Kristie L Rose, Shondra M Pruett-Miller, Vivian Gama
Published 2021-01-01

Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex

by Eric T Hall, Miriam E Dillard, Daniel P Stewart, Yan Zhang, Ben Wagner, Rachel M Levine, Shondra M Pruett-Miller, April Sykes, Jamshid Temirov, Richard E Cheney, Motomi Mori, Camenzind G Robinson, Stacey K Ogden
Published 2021-02-01

The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51.

by Jung Mi Park, Seung Wook Yang, Wei Zhuang, Asim K Bera, Yan Liu, Deepak Gurbani, Sergei J von Hoyningen-Huene, Sadie Miki Sakurada, Haiyun Gan, Shondra M Pruett-Miller, Kenneth D Westover, Malia B Potts
Published 2021-06-01

Schizophrenia-related microdeletion causes defective ciliary motility and brain ventricle enlargement via microRNA-dependent mechanisms in mice

by Tae-Yeon Eom, Seung Baek Han, Jieun Kim, Jay A. Blundon, Yong-Dong Wang, Jing Yu, Kara Anderson, Damian B. Kaminski, Sadie Miki Sakurada, Shondra M. Pruett-Miller, Linda Horner, Ben Wagner, Camenzind G. Robinson, Matthew Eicholtz, Derek C. Rose, Stanislav S. Zakharenko
Published 2020-02-01

Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome

by Andrea J. Cohen, Alina Saiakhova, Olivia Corradin, Jennifer M. Luppino, Katreya Lovrenert, Cynthia F. Bartels, James J. Morrow, Stephen C. Mack, Gursimran Dhillon, Lydia Beard, Lois Myeroff, Matthew F. Kalady, Joseph Willis, James E. Bradner, Ruth A. Keri, Nathan A. Berger, Shondra M. Pruett-Miller, Sanford D. Markowitz, Peter C. Scacheri
Published 2017-02-01

Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL)

by Timothy I. Shaw, Li Dong, Liqing Tian, Chenxi Qian, Yu Liu, Bensheng Ju, Anthony High, Kanisha Kavdia, Vishwajeeth R. Pagala, Bridget Shaner, Deqing Pei, John Easton, Laura J. Janke, Shaina N. Porter, Xiaotu Ma, Cheng Cheng, Shondra M. Pruett-Miller, John Choi, Jiyang Yu, Junmin Peng, Wei Gu, A. Thomas Look, James R. Downing, Jinghui Zhang
Published 2021-03-01

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

by Maged Zeineldin, Sara Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart, Xin Zhou, Jongrye Jeon, Lyra Griffiths, Rosa Nguyen, Jackie Norrie, John Easton, Heather Mulder, Donald Yergeau, Yanling Liu, Jianrong Wu, Collin Van Ryn, Arlene Naranjo, Michael D. Hogarty, Marcin M. Kamiński, Marc Valentine, Shondra M. Pruett-Miller, Alberto Pappo, Jinghui Zhang, Michael R. Clay, Armita Bahrami, Peter Vogel, Seungjae Lee, Anang Shelat, Jay F. Sarthy, Michael P. Meers, Rani E. George, Elaine R. Mardis, Richard K. Wilson, Steven Henikoff, James R. Downing, Michael A. Dyer
Published 2020-02-01