Comparison of Bayesian and frequentist group-sequential clinical trial designs

by Nigel Stallard, Susan Todd, Elizabeth G. Ryan, Simon Gates
Published 2020-01-01

Do we need to adjust for interim analyses in a Bayesian adaptive trial design?

by Elizabeth G. Ryan, Kristian Brock, Simon Gates, Daniel Slade
Published 2020-06-01

Bayesian adaptive designs for multi-arm trials: an orthopaedic case study

by Elizabeth G. Ryan, Sarah E. Lamb, Esther Williamson, Simon Gates
Published 2020-01-01

Bayesian group sequential designs for phase III emergency medicine trials: a case study using the PARAMEDIC2 trial

by Elizabeth G. Ryan, Nigel Stallard, Ranjit Lall, Chen Ji, Gavin D. Perkins, Simon Gates
Published 2020-01-01

Using Bayesian adaptive designs to improve phase III trials: a respiratory care example

by Elizabeth G. Ryan, Julie Bruce, Andrew J. Metcalfe, Nigel Stallard, Sarah E. Lamb, Kert Viele, Duncan Young, Simon Gates
Published 2019-05-01

Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and...

by Geoffrey Warhurst, Graham Dunn, Paul Chadwick, Bronagh Blackwood, Daniel McAuley, Gavin D Perkins, Ronan McMullan, Simon Gates, Andrew Bentley, Duncan Young, Gordon L Carlson, Paul Dark
Published 2015-05-01

Protocol for a randomised controlled trial of Subacromial spacer for Tears Affecting Rotator cuff Tendons: a Randomised, Efficient, Adaptive Clinical Trial in Surgery (START:REACTS...

by Martin Underwood, Nicholas Parsons, Helen Parsons, Jaclyn Brown, James Mason, Simon Gates, Andrew Metcalfe, Elke Gemperle Mannion, Josephine Fox, Rebecca Kearney, Tom Lawrence, Howard Bush, Kerri McGowan, Iftekhar Khan, Charles Hutchinson, Nigel Stallard, Stephen Drew
Published 2020-05-01

Cost-effectiveness of adrenaline for out-of-hospital cardiac arrest

by Felix Achana, Stavros Petrou, Jason Madan, Kamran Khan, Chen Ji, Anower Hossain, Ranjit Lall, Anne-Marie Slowther, Charles D. Deakin, Tom Quinn, Jerry P. Nolan, Helen Pocock, Nigel Rees, Michael Smyth, Simon Gates, Dale Gardiner, Gavin D. Perkins, for the PARAMEDIC2 Collaborators
Published 2020-09-01

Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT

by Gavin D Perkins, Dipesh Mistry, Ranjit Lall, Fang Gao-Smith, Catherine Snelson, Nicholas Hart, Luigi Camporota, James Varley, Coralie Carle, Elankumaran Paramasivam, Beverly Hoddell, Adam de Paeztron, Sukhdeep Dosanjh, Julia Sampson, Laura Blair, Keith Couper, Daniel McAuley, J Duncan Young, Tim Walsh, Bronagh Blackwood, Louise Rose, Sarah E Lamb, Melina Dritsaki, Mandy Maredza, Iftekhar Khan, Stavros Petrou, Simon Gates
Published 2019-09-01

Prehospital randomised assessment of a mechanical compression device in out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised trial and economic evaluation

by Simon Gates, Ranjit Lall, Tom Quinn, Charles D Deakin, Matthew W Cooke, Jessica Horton, Sarah E Lamb, Anne-Marie Slowther, Malcolm Woollard, Andy Carson, Mike Smyth, Kate Wilson, Garry Parcell, Andrew Rosser, Richard Whitfield, Amanda Williams, Rebecca Jones, Helen Pocock, Nicola Brock, John JM Black, John Wright, Kyee Han, Gary Shaw, Laura Blair, Joachim Marti, Claire Hulme, Christopher McCabe, Silviya Nikolova, Zenia Ferreira, Gavin D Perkins
Published 2017-03-01

Adrenaline to improve survival in out-of-hospital cardiac arrest: the PARAMEDIC2 RCT

by Gavin D Perkins, Chen Ji, Felix Achana, John JM Black, Karl Charlton, James Crawford, Adam de Paeztron, Charles Deakin, Mark Docherty, Judith Finn, Rachael T Fothergill, Simon Gates, Imogen Gunson, Kyee Han, Susie Hennings, Jessica Horton, Kamran Khan, Sarah Lamb, John Long, Joshua Miller, Fionna Moore, Jerry Nolan, Lyndsey O’Shea, Stavros Petrou, Helen Pocock, Tom Quinn, Nigel Rees, Scott Regan, Andy Rosser, Charlotte Scomparin, Anne Slowther, Ranjit Lall
Published 2021-04-01