The Contribution of Neutrophils to the Pathogenesis of RSV Bronchiolitis

by Ismail Sebina, Simon Phipps
Published 2020-07-01

Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4.

by Katharine J Goodall, Ivan K H Poon, Simon Phipps, Mark D Hulett
Published 2014-01-01

The Absence of Interferon-β Promotor Stimulator-1 (IPS-1) Predisposes to Bronchiolitis and Asthma-like Pathology in Response to Pneumoviral Infection in Mice

by Jennifer Simpson, Jason P. Lynch, Zhixuan Loh, Vivian Zhang, Rhiannon B. Werder, Kirsten Spann, Simon Phipps
Published 2017-05-01

Asthma is associated with multiple alterations in anti-viral innate signalling pathways.

by Antonia L Pritchard, Olivia J White, Julie G Burel, Melanie L Carroll, Simon Phipps, John W Upham
Published 2014-01-01

TLR2, but not TLR4, is required for effective host defence against Chlamydia respiratory tract infection in early life.

by Emma L Beckett, Simon Phipps, Malcolm R Starkey, Jay C Horvat, Kenneth W Beagley, Paul S Foster, Philip M Hansbro
Published 2012-01-01

Critical Role of Plasmacytoid Dendritic Cells in Regulating Gene Expression and Innate Immune Responses to Human Rhinovirus-16

by Yang Xi, Niamh M. Troy, Denise Anderson, Olga M. Pena, Jason P. Lynch, Simon Phipps, Anthony Bosco, John W. Upham, John W. Upham
Published 2017-10-01

Tissue quality assessment using a novel direct elasticity assessment device (the E-finger): a cadaveric study of prostatectomy dissection.

by Daniel W Good, Ashfaq Khan, Steven Hammer, Paul Scanlan, Wenmiao Shu, Simon Phipps, Simon H Parson, Grant D Stewart, Robert Reuben, S Alan McNeill
Published 2014-01-01

Prevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillance.

by Mona S Awadalla, Jude Fitzgerald, Nicholas H Andrew, Tiger Zhou, Henry Marshall, Ayub Qassim, Mark Hassall, Robert J Casson, Stuart L Graham, Paul R Healey, Ashish Agar, Anna Galanopoulos, Simon Phipps, Angela Chappell, John Landers, Jamie E Craig
Published 2018-01-01

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma

by Jaisy Arikkatt, Md Ashik Ullah, Kirsty Renfree Short, Vivan Zhang, Wan Jun Gan, Zhixuan Loh, Rhiannon B Werder, Jennifer Simpson, Peter D Sly, Stuart B Mazzone, Kirsten M Spann, Manuel AR Ferreira, John W Upham, Maria B Sukkar, Simon Phipps
Published 2017-01-01

Modulation of Vagal Sensory Neurons via High Mobility Group Box-1 and Receptor for Advanced Glycation End Products: Implications for Respiratory Viral Infections

by Stuart B. Mazzone, Seung-Kwon Yang, Jennifer A. Keller, Juste Simanauskaite, Jaisy Arikkatt, Matthew J. Fogarty, Aung Aung Kywe Moe, Chen Chen, Matthew W. Trewella, Luyi Tian, Matthew E. Ritchie, Brendan Y. Chua, Simon Phipps, Kirsty R. Short, Alice E. McGovern
Published 2021-09-01

Author Correction: Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication

by Wen Juan Tu, Robert D. McCuaig, Michelle Melino, Daniel J. Rawle, Thuy T. Le, Kexin Yan, Andreas Suhrbier, Rebecca L. Johnston, Lambros T. Koufariotis, Nicola Waddell, Emily M. Cross, Sofiya Tsimbalyuk, Amanda Bain, Elizabeth Ahern, Natasha Collinson, Simon Phipps, Jade K. Forwood, Nabila Seddiki, Sudha Rao
Published 2021-07-01

Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication

by Wen Juan Tu, Robert D. McCuaig, Michelle Melino, Daniel J. Rawle, Thuy T. Le, Kexin Yan, Andreas Suhrbier, Rebecca L. Johnston, Lambros T. Koufariotis, Nicola Waddell, Emily M. Cross, Sofiya Tsimbalyuk, Amanda Bain, Elizabeth Ahern, Natasha Collinson, Simon Phipps, Jade K. Forwood, Nabila Seddiki, Sudha Rao
Published 2021-05-01

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling.

by Zhixuan Loh, Jennifer Simpson, Ashik Ullah, Vivian Zhang, Wan J Gan, Jason P Lynch, Rhiannon B Werder, Al Amin Sikder, Katie Lane, Choon Boon Sim, Enzo Porrello, Stuart B Mazzone, Peter D Sly, Raymond J Steptoe, Kirsten M Spann, Maria B Sukkar, John W Upham, Simon Phipps
Published 2020-07-01

A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variants

by Katina D Hulme, Anjana C Karawita, Cassandra Pegg, Myrna JM Bunte, Helle Bielefeldt-Ohmann, Conor J Bloxham, Silvie Van den Hoecke, Yin Xiang Setoh, Bram Vrancken, Monique Spronken, Lauren E Steele, Nathalie AJ Verzele, Kyle R Upton, Alexander A Khromykh, Keng Yih Chew, Maria Sukkar, Simon Phipps, Kirsty R Short
Published 2021-02-01

Bone Marrow Regulatory T Cells Are a Unique Population, Supported by Niche-Specific Cytokines and Plasmacytoid Dendritic Cells, and Required for Chronic Graft-Versus-Host Disease C...

by Jemma Nicholls, Benjamin Cao, Benjamin Cao, Laetitia Le Texier, Laura Yan Xiong, Christopher R. Hunter, Genesis Llanes, Ethan G. Aguliar, Wayne A. Schroder, Simon Phipps, Jason P. Lynch, Huimin Cao, Huimin Cao, Shen Y. Heazlewood, Shen Y. Heazlewood, Brenda Williams, Brenda Williams, Andrew D. Clouston, Christian M. Nefzger, Christian M. Nefzger, Christian M. Nefzger, Jose M. Polo, Jose M. Polo, Jose M. Polo, Susan K. Nilsson, Susan K. Nilsson, Bruce R. Blazar, Kelli P. A. MacDonald
Published 2021-09-01