Human Double-Negative Regulatory T-Cells Induce a Metabolic and Functional Switch in Effector T-Cells by Suppressing mTOR Activity

by Tabea Haug, Michael Aigner, Moritz M. Peuser, Carolin D. Strobl, Kai Hildner, Dimitrios Mougiakakos, Heiko Bruns, Andreas Mackensen, Simon Völkl
Published 2019-04-01

Thrombopoietin receptor agonists for acquired thrombocytopenia following anti-CD19 CAR-T-cell therapy: a case report

by Regina Jitschin, Simon Völkl, Andreas Mackensen, Dimitrios Mougiakakos, Daniela Schmidt, Maike Büttner-Herold, Rebecca Baur, Soraya Kharboutli, Andrej Stoll, Wolf Rösler
Published 2021-07-01

CD33/CD3-bispecific T-cell engaging (BiTE®) antibody construct targets monocytic AML myeloid-derived suppressor cells

by Regina Jitschin, Domenica Saul, Martina Braun, Sehmus Tohumeken, Simon Völkl, Roman Kischel, Michael Lutteropp, Cedric Dos Santos, Andreas Mackensen, Dimitrios Mougiakakos
Published 2018-11-01

Circulating Adaptive Immune Cells Expressing the Gut Homing Marker α4β7 Integrin Are Decreased in COVID-19

by Tanja M. Müller, Emily Becker, Maximilian Wiendl, Lisa Lou Schulze, Caroline Voskens, Simon Völkl, Andreas E. Kremer, Markus F. Neurath, Sebastian Zundler
Published 2021-04-01

The Oncometabolite 5′-Deoxy-5′-Methylthioadenosine Blocks Multiple Signaling Pathways of NK Cell Activation

by Benedikt Jacobs, Sebastian Schlögl, Carolin Dorothea Strobl, Simon Völkl, Andrej Stoll, Dimitrios Mougiakakos, Karl-Johan Malmberg, Karl-Johan Malmberg, Karl-Johan Malmberg, Andreas Mackensen, Michael Aigner
Published 2020-10-01

Vascular occlusion by neutrophil extracellular traps in COVID-19

by Moritz Leppkes, Jasmin Knopf, Elisabeth Naschberger, Aylin Lindemann, Jeeshan Singh, Irmgard Herrmann, Michael Stürzl, Léonie Staats, Aparna Mahajan, Christine Schauer, Anita N. Kremer, Simon Völkl, Kerstin Amann, Katja Evert, Christina Falkeis, Andreas Wehrfritz, Ralf J. Rieker, Arndt Hartmann, Andreas E. Kremer, Markus F. Neurath, Luis E. Muñoz, Georg Schett, Martin Herrmann
Published 2020-08-01