Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System

by Richard Hoehn, Marlene Monse, Ella Pohl, Sina Wranik, Barbara Wilker, Simone Keitsch, Matthias Soddemann, Johannes Kornhuber, Marcus Kohnen, Michael J. Edwards, Heike Grassmé, Erich Gulbins
Published 2016-07-01

Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis

by Shaghayegh Tavakoli Tabazavareh, Aaron Seitz, Peter Jernigan, Carolin Sehl, Simone Keitsch, Stephan Lang, Barbara C. Kahl, Michael Edwards, Heike Grassmé, Erich Gulbins, Katrin Anne Becker
Published 2016-05-01

Inhaled sphingosine has no adverse side effects in isolated ventilated and perfused pig lungs

by Henning Carstens, Katharina Kalka, Rabea Verhaegh, Fabian Schumacher, Matthias Soddemann, Barbara Wilker, Simone Keitsch, Carolin Sehl, Burkhard Kleuser, Thorsten Wahlers, Gerald Reiner, Achim Koch, Ursula Rauen, Erich Gulbins, Markus Kamler
Published 2021-09-01

Inhibition of PI-3-K and AKT Amplifies Kv1.3 Inhibitor-Induced Death of Human T Leukemia Cells

by Tim Bergermann, Lukas Born, Fiona Ferguson, Paula Latkovic, Alexandra Scheul, Nina Sonnenschein, Luigi Leanza, Simone Keitsch, Carolin Sehl, Barbara Wilker, Michael J. Edwards, Mario Zoratti, Cristina Paradisi, Markus Kohnen, Ildiko Szabo, Katrin Anne Becker, Alexander Carpinteiro
Published 2019-12-01

Clinical Development of Sphingosine as Anti-Bacterial Drug: Inhalation of Sphingosine in Mini Pigs has no Adverse Side Effects

by Henning Carstens, Fabian Schumacher, Simone Keitsch, Melanie Kramer, Claudine Kühn, Carolin Sehl, Matthias Soddemann, Barbara Wilker, Daniel Herrmann, Ashraf Swaidan, Burkhard Kleuser, Rabea Verhaegh, Gero Hilken, Michael J. Edwards, Marko Dubicanac, Alexander Carpinteiro, Andreas Wissmann, Katrin Anne Becker, Markus Kamler, Erich Gulbins
Published 2019-12-01