Identification of HSP90 inhibitors as a novel class of senolytics

by Heike Fuhrmann-Stroissnigg, Yuan Yuan Ling, Jing Zhao, Sara J. McGowan, Yi Zhu, Robert W. Brooks, Diego Grassi, Siobhan Q. Gregg, Jennifer L. Stripay, Akaitz Dorronsoro, Lana Corbo, Priscilla Tang, Christina Bukata, Nadja Ring, Mauro Giacca, Xuesen Li, Tamara Tchkonia, James L. Kirkland, Laura J. Niedernhofer, Paul D. Robbins
Published 2017-09-01

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging

by Andria R. Robinson, Matthew J. Yousefzadeh, Tania A. Rozgaja, Jin Wang, Xuesen Li, Jeremy S. Tilstra, Chelsea H. Feldman, Siobhán Q. Gregg, Caroline H. Johnson, Erin M. Skoda, Marie-Céline Frantz, Harris Bell-Temin, Hannah Pope-Varsalona, Aditi U. Gurkar, Luigi A. Nasto, Renã A.S. Robinson, Heike Fuhrmann-Stroissnigg, Jolanta Czerwinska, Sara J. McGowan, Nadiezhda Cantu-Medellin, Jamie B. Harris, Salony Maniar, Mark A. Ross, Christy E. Trussoni, Nicholas F. LaRusso, Eugenia Cifuentes-Pagano, Patrick J. Pagano, Barbara Tudek, Nam V. Vo, Lora H. Rigatti, Patricia L. Opresko, Donna B. Stolz, Simon C. Watkins, Christin E. Burd, Claudette M. St. Croix, Gary Siuzdak, Nathan A. Yates, Paul D. Robbins, Yinsheng Wang, Peter Wipf, Eric E. Kelley, Laura J. Niedernhofer
Published 2018-07-01