Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91

by Mette Trauelsen, Elisabeth Rexen Ulven, Siv A. Hjorth, Matjaz Brvar, Claudia Monaco, Thomas M. Frimurer, Thue W. Schwartz
Published 2017-12-01

Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

by Roland Baumgartner, Felipe B. Casagrande, Randi B. Mikkelsen, Martin Berg, Konstantinos A. Polyzos, Maria J. Forteza, Aastha Arora, Thue W. Schwartz, Siv A. Hjorth, Daniel F. J. Ketelhuth
Published 2021-06-01

Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling

by Mette Trauelsen, Thomas K. Hiron, Da Lin, Jacob E. Petersen, Billy Breton, Anna Sofie Husted, Siv A. Hjorth, Asuka Inoue, Thomas M. Frimurer, Michel Bouvier, Chris A. O’Callaghan, Thue W. Schwartz
Published 2021-06-01

Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

by Kaare V. Grunddal, Thi A. Diep, Natalia Petersen, Iain R. Tough, Louise J. Skov, Lingzhi Liu, Jesse A. Buijink, Franziska Mende, Chunyu Jin, Sara L. Jepsen, Louis M.E. Sørensen, Michael P. Achiam, Rune B. Strandby, Anders Bach, Bolette Hartmann, Thomas M. Frimurer, Siv A. Hjorth, Michel Bouvier, Helen Cox, Birgitte Holst
Published 2021-07-01