Chemoenzymatic synthesis of 3-ethyl-2,5-dimethylpyrazine by L-threonine 3-dehydrogenase and 2-amino-3-ketobutyrate CoA ligase/L-threonine aldolase

by Tomoharu Motoyama, Shogo Nakano, Fumihito Hasebe, Ryo Miyata, Shigenori Kumazawa, Noriyuki Miyoshi, Sohei Ito
Published 2021-07-01

Computational Analysis Reveals a Critical Point Mutation in the <i>N</i>-Terminal Region of the Signaling Lymphocytic Activation Molecule Responsible for the Cross-Species Infectio...

by Yuta Yamamoto, Shogo Nakano, Fumio Seki, Yasuteru Shigeta, Sohei Ito, Hiroaki Tokiwa, Makoto Takeda
Published 2021-02-01

In Vitro and In Silico Studies of the Molecular Interactions of Epigallocatechin-3-O-gallate (EGCG) with Proteins That Explain the Health Benefits of Green Tea

by Koichi Saeki, Sumio Hayakawa, Shogo Nakano, Sohei Ito, Yumiko Oishi, Yasuo Suzuki, Mamoru Isemura
Published 2018-05-01

Computational Molecular Docking and X-ray Crystallographic Studies of Catechins in New Drug Design Strategies

by Shogo Nakano, Shin-ichi Megro, Tadashi Hase, Takuji Suzuki, Mamoru Isemura, Yoriyuki Nakamura, Sohei Ito
Published 2018-08-01

Elucidation of Molecular Mechanism of a Selective PPARα Modulator, Pemafibrate, through Combinational Approaches of X-ray Crystallography, Thermodynamic Analysis, and First-Princip...

by Mayu Kawasaki, Akira Kambe, Yuta Yamamoto, Sundaram Arulmozhiraja, Sohei Ito, Yoshimi Nakagawa, Hiroaki Tokiwa, Shogo Nakano, Hitoshi Shimano
Published 2020-01-01

Genome-wide screening of salt tolerant genes by activation-tagging using dedifferentiated calli of Arabidopsis and its application to finding gene for Myo-inositol-1-p-synthase.

by Aftab Ahmad, Yasuo Niwa, Shingo Goto, Kyoko Kobayashi, Masanori Shimizu, Sohei Ito, Yumiko Usui, Tsutomu Nakayama, Hirokazu Kobayashi
Published 2015-01-01

AirID, a novel proximity biotinylation enzyme, for analysis of protein–protein interactions

by Kohki Kido, Satoshi Yamanaka, Shogo Nakano, Kou Motani, Souta Shinohara, Akira Nozawa, Hidetaka Kosako, Sohei Ito, Tatsuya Sawasaki
Published 2020-05-01

The role of IL-6 in pathogenesis of abdominal aortic aneurysm in mice.

by Michihide Nishihara, Hiroki Aoki, Satoko Ohno, Aya Furusho, Saki Hirakata, Norifumi Nishida, Sohei Ito, Makiko Hayashi, Tsutomu Imaizumi, Yoshihiro Fukumoto
Published 2017-01-01

Binding of Catechins to Staphylococcal Enterotoxin A

by Yuko Shimamura, Mio Utsumi, Chikako Hirai, Shogo Nakano, Sohei Ito, Ai Tsuji, Takeshi Ishii, Takahiro Hosoya, Toshiyuki Kan, Norio Ohashi, Shuichi Masuda
Published 2018-05-01

Therapeutic Effect of Rapamycin on Aortic Dissection in Mice

by Makiko Hayashi-Hori, Hiroki Aoki, Miho Matsukuma, Ryohei Majima, Yohei Hashimoto, Sohei Ito, Saki Hirakata, Norifumi Nishida, Aya Furusho, Satoko Ohno-Urabe, Yoshihiro Fukumoto
Published 2020-05-01

MRTF-A promotes angiotensin II-induced inflammatory response and aortic dissection in mice.

by Sohei Ito, Yohei Hashimoto, Ryohei Majima, Eichi Nakao, Hiroki Aoki, Michihide Nishihara, Satoko Ohno-Urabe, Aya Furusho, Saki Hirakata, Norifumi Nishida, Makiko Hayashi, Koichiro Kuwahara, Yoshihiro Fukumoto
Published 2020-01-01

Genetic Deletion of Socs3 in Smooth Muscle Cells Ameliorates Aortic Dissection in Mice

by Saki Hirakata, MD, Hiroki Aoki, MD, PhD, Satoko Ohno-Urabe, MD, PhD, Michihide Nishihara, MD, PhD, Aya Furusho, MD, PhD, Norifumi Nishida, MD, Sohei Ito, MD, Makiko Hayashi, MD, Hideo Yasukawa, MD, PhD, Tsutomu Imaizumi, MD, PhD, Sinichi Hiromatsu, MD, PhD, Hiroyuki Tanaka, MD, PhD, Yoshihiro Fukumoto, MD, PhD
Published 2020-02-01