α-synuclein impairs autophagosome maturation through abnormal actin stabilization.

by Souvarish Sarkar, Abby L Olsen, Katja Sygnecka, Kelly M Lohr, Mel B Feany
Published 2021-02-01

Oligomerization of Lrrk controls actin severing and α-synuclein neurotoxicity in vivo

by Souvarish Sarkar, Farah Bardai, Abby L. Olsen, Kelly M. Lohr, Ying-Yi Zhang, Mel B. Feany
Published 2021-05-01

Role of the Fyn-PKCδ signaling in SE-induced neuroinflammation and epileptogenesis in experimental models of temporal lobe epilepsy

by Shaunik Sharma, Steven Carlson, Sreekanth Puttachary, Souvarish Sarkar, Lucas Showman, Marson Putra, Anumantha G. Kanthasamy, Thimmasettappa Thippeswamy
Published 2018-02-01

Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

by Souvarish Sarkar, Michael A. Murphy, Eric B. Dammer, Abby L. Olsen, Srikant Rangaraju, Ernest Fraenkel, Mel B. Feany
Published 2020-12-01

Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells

by Souvarish Sarkar, Souvarish Sarkar, Eric B. Dammer, Emir Malovic, Abby L. Olsen, Syed Ali Raza, Tianwen Gao, Hailian Xiao, Danielle L. Oliver, Duc Duong, Valerie Joers, Nicholas Seyfried, Nicholas Seyfried, Meixiang Huang, Thomas Kukar, Thomas Kukar, Malú G. Tansey, Anumantha G. Kanthasamy, Srikant Rangaraju
Published 2020-01-01

Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events

by Neeraj Singh, Vivek Lawana, Jie Luo, Phang Phong, Ahmed Abdalla, Bharathi Palanisamy, Dharmin Rokad, Souvarish Sarkar, Huajun Jin, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy
Published 2018-09-01

Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease

by Richard Gordon, Neeraj Singh, Vivek Lawana, Anamitra Ghosh, Dilshan S. Harischandra, Huajun Jin, Colleen Hogan, Souvarish Sarkar, Dharmin Rokad, Nikhil Panicker, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy
Published 2016-09-01