The Ionic and hydrophobic interactions are required for the auto activation of cysteine proteases of Plasmodium falciparum.

by Srinivasan Sundararaj, Deepak Singh, Ajay K Saxena, Kapil Vashisht, Puran S Sijwali, Rajnikant Dixit, Kailash C Pandey
Published 2012-01-01

Cross-talk between malarial cysteine proteases and falstatin: the BC loop as a hot-spot target.

by Srinivasan Sundararaj, Ajay K Saxena, Ruby Sharma, Kapil Vashisht, Supriya Sharma, Anup Anvikar, Rajnikant Dixit, Philip J Rosenthal, Kailash C Pandey
Published 2014-01-01

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

by Catarina F. Almeida, Srinivasan Sundararaj, Jérôme Le Nours, T. Praveena, Benjamin Cao, Satvika Burugupalli, Dylan G. M. Smith, Onisha Patel, Manfred Brigl, Daniel G. Pellicci, Spencer J. Williams, Adam P. Uldrich, Dale I. Godfrey, Jamie Rossjohn
Published 2019-11-01

Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation

by Mark M. Hughes, Alexander Hooftman, Stefano Angiari, Padmaja Tummala, Zbigniew Zaslona, Marah C. Runtsch, Anne F. McGettrick, Caroline E. Sutton, Ciana Diskin, Melissa Rooke, Shuhei Takahashi, Srinivasan Sundararaj, Marco G. Casarotto, Jane E. Dahlstrom, Eva M. Palsson-McDermott, Sinead C. Corr, Kingston H.G. Mills, Roger J.S. Preston, Nouri Neamati, Yiyue Xie, Jonathan B. Baell, Philip G. Board, Luke A.J. O’Neill
Published 2019-10-01