Stanford V
Stanford V (usually spoken as ''Stanford Five''), is a
chemotherapy regimen (with accompanying
radiation therapy) intended as a
first-line treatment for
Hodgkin lymphoma. The regimen was developed in 1988, with the objective of maintaining a high remission rate while reducing the incidence of acute and long term toxicity, pulmonary damage, and sterility observed in alternative treatment regimens such as
ABVD. The chemical agents used are:
* A
mustard derivative such as
cyclophosphamide,
chlormethine or
ifosfamide
*
Doxorubicin, an anti-tumor
antibiotic
*
Vinblastine, an
alkaloid cell toxin
*
Vincristine, another alkaloid cell toxin
*
Bleomycin, another anti-tumor antibiotic
*
Etoposide, a
DNA toxin
*
Prednisone, a
corticosteroid
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