A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.

by Nuruddeen D Lewis, Lori A Patnaude, Josephine Pelletier, Donald J Souza, Susan M Lukas, F James King, Jonathan D Hill, Dimitria E Stefanopoulos, Kelli Ryan, Sudha Desai, Donna Skow, Stefan G Kauschke, Andre Broermann, Daniel Kuzmich, Christian Harcken, Eugene R Hickey, Louise K Modis
Published 2014-01-01