Involvement of Innate Immune Receptors in the Resolution of Acute Hepatitis B in Woodchucks

by Manasa Suresh, Bin Li, Marta G. Murreddu, Severin O. Gudima, Stephan Menne
Published 2021-07-01

AIC649 Induces a Bi-Phasic Treatment Response in the Woodchuck Model of Chronic Hepatitis B.

by Daniela Paulsen, Olaf Weber, Helga Ruebsamen-Schaeff, Bud C Tennant, Stephan Menne
Published 2015-01-01

Innate and adaptive immunity associated with resolution of acute woodchuck hepatitis virus infection in adult woodchucks.

by Manasa Suresh, Stefanie Czerwinski, Marta G Murreddu, Bhaskar V Kallakury, Ashika Ramesh, Severin O Gudima, Stephan Menne
Published 2019-12-01

Agonistic Activation of Cytosolic DNA Sensing Receptors in Woodchuck Hepatocyte Cultures and Liver for Inducing Antiviral Effects

by Manasa Suresh, Bin Li, Xu Huang, Kyle E. Korolowicz, Marta G. Murreddu, Severin O. Gudima, Stephan Menne
Published 2021-10-01

Suitability of the woodchuck HCC as a preclinical model for evaluation of intra‐arterial therapies

by Alexander Y. Kim, Joseph H. Yacoub, David H. Field, Byoung Uk Park, Bhaskar Kallakury, Kyle E. Korolowicz, Stephan Menne
Published 2020-03-01

Treatment with the Immunomodulator AIC649 in Combination with Entecavir Produces Antiviral Efficacy in the Woodchuck Model of Chronic Hepatitis B

by Kyle E. Korolowicz, Manasa Suresh, Bin Li, Xu Huang, Changsuek Yon, Xuebing Leng, Bhaskar V. Kallakury, Robin D. Tucker, Stephan Menne
Published 2021-04-01

Dose-Dependent Sorafenib-Induced Immunosuppression Is Associated with Aberrant NFAT Activation and Expression of PD-1 in T Cells

by Renuka V. Iyer, Orla Maguire, Minhyung Kim, Leslie I. Curtin, Sandra Sexton, Daniel T. Fisher, Sarah A. Schihl, Gerald Fetterly, Stephan Menne, Hans Minderman
Published 2019-05-01

Combination Treatment with the Vimentin-Targeting Antibody hzVSF and Tenofovir Suppresses Woodchuck Hepatitis Virus Infection in Woodchucks

by Kyle E. Korolowicz, Manasa Suresh, Bin Li, Xu Huang, Changsuek Yon, Bhaskar V. Kallakury, Kyoung-pil Lee, Sungman Park, Yoon-Won Kim, Stephan Menne
Published 2021-09-01

Liver‐Targeted Toll‐Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus

by Kyle E. Korolowizc, Bin Li, Xu Huang, Changsuek Yon, Evelyn Rodrigo, Manny Corpuz, David M. Plouffe, Bhaskar V. Kallakury, Manasa Suresh, Tom Y.‐H. Wu, Andrew T. Miller, Stephan Menne
Published 2019-10-01

Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon‐α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus

by Stephan Menne, Steffen Wildum, Guido Steiner, Manasa Suresh, Kyle Korolowicz, Maria Balarezo, Changsuek Yon, Marta Murreddu, Xupeng Hong, Bhaskar V. Kallakury, Robin Tucker, Song Yang, John A.T. Young, Hassan Javanbakht
Published 2020-06-01

Antiviral Efficacy and Host Immune Response Induction during Sequential Treatment with SB 9200 Followed by Entecavir in Woodchucks.

by Manasa Suresh, Kyle E Korolowicz, Maria Balarezo, Radhakrishnan P Iyer, Seetharamaiyer Padmanabhan, Dillon Cleary, Rayomand Gimi, Anjaneyulu Sheri, Changsuek Yon, Bhaskar V Kallakury, Robin D Tucker, Nezam Afdhal, Stephan Menne
Published 2017-01-01

The Genome Sequence of the Eastern Woodchuck (Marmota monax) – A Preclinical Animal Model for Chronic Hepatitis B

by Tyler S. Alioto, Fernando Cruz, Jèssica Gómez-Garrido, Miriam Triyatni, Marta Gut, Leonor Frias, Anna Esteve-Codina, Stephan Menne, Anna Kiialainen, Nadine Kumpesa, Fabian Birzele, Roland Schmucki, Ivo G. Gut, Olivia Spleiss
Published 2019-12-01

Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B.

by Kyle E Korolowicz, Radhakrishnan P Iyer, Stefanie Czerwinski, Manasa Suresh, Junming Yang, Seetharamaiyer Padmanabhan, Anjaneyulu Sheri, Rajendra K Pandey, Jeffrey Skell, Judith K Marquis, Bhaskar V Kallakury, Robin D Tucker, Stephan Menne
Published 2016-01-01

Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B.

by Simon P Fletcher, Daniel J Chin, Lore Gruenbaum, Hans Bitter, Erik Rasmussen, Palanikumar Ravindran, David C Swinney, Fabian Birzele, Roland Schmucki, Stefan H Lorenz, Erhard Kopetzki, Jade Carter, Miriam Triyatni, Linta M Thampi, Junming Yang, Dalal AlDeghaither, Marta G Murreddu, Paul Cote, Stephan Menne
Published 2015-09-01

Correction: Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B.

by Simon P Fletcher, Daniel J Chin, Lore Gruenbaum, Hans Bitter, Erik Rasmussen, Palanikumar Ravindran, David C Swinney, Fabian Birzele, Roland Schmucki, Stefan H Lorenz, Erhard Kopetzki, Jade Carter, Miriam Triyatni, Linta M Thampi, Junming Yang, Dalal AlDeghaither, Marta G Murreddu, Paul Cote, Stephan Menne
Published 2016-03-01

Safety and efficacy of anti-PD-L1 therapy in the woodchuck model of HBV infection.

by Scott Balsitis, Volodymyr Gali, Pamela J Mason, Susan Chaniewski, Steven M Levine, Michael J Wichroski, Michael Feulner, Yunling Song, Karen Granaldi, James K Loy, Chris M Thompson, Jacob A Lesniak, Catherine Brockus, Narendra Kishnani, Stephan Menne, Mark I Cockett, Renuka Iyer, Stephen W Mason, Daniel J Tenney
Published 2018-01-01