TCR Recognition of Peptide–MHC-I: Rule Makers and Breakers

by Christopher Szeto, Christian A. Lobos, Andrea T. Nguyen, Stephanie Gras
Published 2021-12-01

Protein purification and crystallization of HLA-A∗02:01 in complex with SARS-CoV-2 peptides

by Demetra S.M. Chatzileontiadou, Christopher Szeto, Dhilshan Jayasinghe, Stephanie Gras
Published 2021-09-01

The Many Faces of CD4⁺ T Cells: Immunological and Structural Characteristics

by Demetra S. M. Chatzileontiadou, Hannah Sloane, Andrea T. Nguyen, Stephanie Gras, Emma J. Grant
Published 2021-12-01

SARS-CoV-2 Spike-Derived Peptides Presented by HLA Molecules

by Andrea T. Nguyen, Christopher Szeto, Dhilshan Jayasinghe, Christian A. Lobos, Hanim Halim, Demetra S. M. Chatzileontiadou, Emma J. Grant, Stephanie Gras
Published 2021-05-01

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

by Kok Fei Chan, Benjamin S. Gully, Stephanie Gras, Dennis X. Beringer, Lars Kjer-Nielsen, Jonathan Cebon, James McCluskey, Weisan Chen, Jamie Rossjohn
Published 2018-03-01

Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans

by Emma J. Grant, Tracy M. Josephs, Liyen Loh, E. Bridie Clemens, Sneha Sant, Mandvi Bharadwaj, Weisan Chen, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska
Published 2018-12-01

Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection

by Sneha Sant, Ludivine Grzelak, Ludivine Grzelak, Zhongfang Wang, Angela Pizzolla, Marios Koutsakos, Jane Crowe, Thomas Loudovaris, Stuart I. Mannering, Glen P. Westall, Linda M. Wakim, Jamie Rossjohn, Jamie Rossjohn, Jamie Rossjohn, Stephanie Gras, Stephanie Gras, Michael Richards, Jianqing Xu, Paul G. Thomas, Liyen Loh, Thi H. O. Nguyen, Katherine Kedzierska
Published 2018-06-01

Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection

by Elodie Picarda, Séverine Bézie, Lorena Usero, Jason Ossart, Marine Besnard, Hanim Halim, Klara Echasserieau, Claire Usal, Jamie Rossjohn, Karine Bernardeau, Stéphanie Gras, Carole Guillonneau
Published 2019-12-01

Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition

by Christopher Szeto, Joseph I. Bloom, Hannah Sloane, Christian A. Lobos, James Fodor, Dhilshan Jayasinghe, Demetra S. M. Chatzileontiadou, Emma J. Grant, Ashley M. Buckle, Stephanie Gras
Published 2020-09-01

Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope.

by Alex T Chen, Markus Cornberg, Stephanie Gras, Carole Guillonneau, Jamie Rossjohn, Andrew Trees, Sebastien Emonet, Juan C de la Torre, Raymond M Welsh, Liisa K Selin
Published 2012-01-01

Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.

by Sophie A Valkenburg, Stephanie Gras, Carole Guillonneau, Nicole L La Gruta, Paul G Thomas, Anthony W Purcell, Jamie Rossjohn, Peter C Doherty, Stephen J Turner, Katherine Kedzierska
Published 2010-08-01

The presentation of SARS-CoV-2 peptides by the common HLA-A∗02:01 molecule

by Christopher Szeto, Demetra S.M. Chatzileontiadou, Andrea T. Nguyen, Hannah Sloane, Christian A. Lobos, Dhilshan Jayasinghe, Hanim Halim, Corey Smith, Alan Riboldi-Tunnicliffe, Emma J. Grant, Stephanie Gras
Published 2021-02-01

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

by Stephanie Gras, Ildiko Van Rhijn, Adam Shahine, Tan-Yun Cheng, Mugdha Bhati, Li Lynn Tan, Hanim Halim, Kathryn D. Tuttle, Laurent Gapin, Jérôme Le Nours, D. Branch Moody, Jamie Rossjohn
Published 2016-10-01

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

by Adam Shahine, Peter Reinink, Josephine F. Reijneveld, Stephanie Gras, Mira Holzheimer, Tan-Yun Cheng, Adriaan J. Minnaard, John D. Altman, Steffi Lenz, Jacques Prandi, Joanna Kubler-Kielb, D. Branch Moody, Jamie Rossjohn, Ildiko Van Rhijn
Published 2019-01-01

Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens

by Jérôme Le Nours, T. Praveena, Daniel G. Pellicci, Nicholas A. Gherardin, Fiona J. Ross, Ricky T. Lim, Gurdyal S. Besra, Santosh Keshipeddy, Stewart K. Richardson, Amy R. Howell, Stephanie Gras, Dale I. Godfrey, Jamie Rossjohn, Adam P. Uldrich
Published 2016-02-01

Structural and regulatory diversity shape HLA-C protein expression levels

by Gurman Kaur, Stephanie Gras, Jesse I. Mobbs, Julian P. Vivian, Adrian Cortes, Thomas Barber, Subita Balaram Kuttikkatte, Lise Torp Jensen, Kathrine E. Attfield, Calliope A. Dendrou, Mary Carrington, Gil McVean, Anthony W. Purcell, Jamie Rossjohn, Lars Fugger
Published 2017-06-01

HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells.

by Sneha Sant, Sergio M Quiñones-Parra, Marios Koutsakos, Emma J Grant, Thomas Loudovaris, Stuart I Mannering, Jane Crowe, Carolien E van de Sandt, Guus F Rimmelzwaan, Jamie Rossjohn, Stephanie Gras, Liyen Loh, Thi H O Nguyen, Katherine Kedzierska
Published 2020-08-01

Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients

by Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Jeremy Chase Crawford, Liyen Loh, Sneha Sant, Ludivine Grzelak, Emma K. Allen, Tim Brahm, E. Bridie Clemens, Maria Auladell, Luca Hensen, Zhongfang Wang, Simone Nüssing, Xiaoxiao Jia, Patrick Günther, Adam K. Wheatley, Stephen J. Kent, Malet Aban, Yi-Mo Deng, Karen L. Laurie, Aeron C. Hurt, Stephanie Gras, Jamie Rossjohn, Jane Crowe, Jianqing Xu, David Jackson, Lorena E. Brown, Nicole La Gruta, Weisan Chen, Peter C. Doherty, Stephen J. Turner, Tom C. Kotsimbos, Paul G. Thomas, Allen C. Cheng, Katherine Kedzierska
Published 2021-05-01

CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph

by Luca Hensen, Patricia T. Illing, E. Bridie Clemens, Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Nicole A. Mifsud, Andrea T. Nguyen, Christopher Szeto, Brendon Y. Chua, Hanim Halim, Simone Rizzetto, Fabio Luciani, Liyen Loh, Emma J. Grant, Phillipa M. Saunders, Andrew G. Brooks, Steve Rockman, Tom C. Kotsimbos, Allen C. Cheng, Michael Richards, Glen P. Westall, Linda M. Wakim, Thomas Loudovaris, Stuart I. Mannering, Michael Elliott, Stuart G. Tangye, David C. Jackson, Katie L. Flanagan, Jamie Rossjohn, Stephanie Gras, Jane Davies, Adrian Miller, Steven Y. C. Tong, Anthony W. Purcell, Katherine Kedzierska
Published 2021-05-01