Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs)

by Stephen Safe, Un-ho Jin, Hyejin Park, Robert S. Chapkin, Arul Jayaraman
Published 2020-09-01

NR4A1 Ligands as Potent Inhibitors of Breast Cancer Cell and Tumor Growth

by Keshav Karki, Kumaravel Mohankumar, Abigail Schoeller, Gregory Martin, Rupesh Shrestha, Stephen Safe
Published 2021-05-01

Aspirin inhibits colon cancer cell and tumor growth and downregulates specificity protein (Sp) transcription factors.

by Satya Pathi, Indira Jutooru, Gayathri Chadalapaka, Vijayalekshmi Nair, Syng-Ook Lee, Stephen Safe
Published 2012-01-01

Broussochalcone A Is a Novel Inhibitor of the Orphan Nuclear Receptor NR4A1 and Induces Apoptosis in Pancreatic Cancer Cells

by Hyo-Seon Lee, Soo-Hyun Kim, Bo-Mi Kim, Stephen Safe, Syng-Ook Lee
Published 2021-04-01

Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization.

by Wei Ying, Srikanth Kanameni, Cheng-An Chang, Vijayalekshmi Nair, Stephen Safe, Fuller W Bazer, Beiyan Zhou
Published 2014-01-01

Activation of COUP-TFI by a Novel Diindolylmethane Derivative

by Kyungsil Yoon, Chien-Cheng Chen, Asuka A. Orr, Patricia N. Barreto, Phanourios Tamamis, Stephen Safe
Published 2019-03-01

Omeprazole Inhibits Glioblastoma Cell Invasion and Tumor Growth

by Un-Ho Jin, Sharon K. Michelhaugh, Lisa A. Polin, Rupesh Shrestha, Sandeep Mittal, Stephen Safe
Published 2020-07-01

Nuclear Receptor 4A1 (NR4A1) as a Drug Target for Renal Cell Adenocarcinoma.

by Erik Hedrick, Syng-Ook Lee, Gyungeun Kim, Maen Abdelrahim, Un-Ho Jin, Stephen Safe, Ala Abudayyeh
Published 2015-01-01

Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1).

by Cedar H A Boakye, Ravi Doddapaneni, Punit P Shah, Apurva R Patel, Chandraiah Godugu, Stephen Safe, Santosh K Katiyar, Mandip Singh
Published 2013-01-01

Role of metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) in pancreatic cancer.

by Yating Cheng, Parisa Imanirad, Indira Jutooru, Erik Hedrick, Un-Ho Jin, Aline Rodrigues Hoffman, Jeann Leal de Araujo, Benjamin Morpurgo, Andrei Golovko, Stephen Safe
Published 2018-01-01

The Transcriptional Repressor ZBTB4 Regulates EZH2 Through a MicroRNA-ZBTB4-Specificity Protein Signaling Axis

by Won Seok Yang, Gayathri Chadalapaka, Sung-Gook Cho, Syng-ook Lee, Un-Ho Jin, Indira Jutooru, Kwangmin Choi, Yuet-Kin Leung, Shuk-Mei Ho, Stephen Safe, Kyounghyun Kim
Published 2014-12-01

Environmental levels and toxicological potencies of a novel mixed halogenated carbazole

by Miren Pena-Abaurrea, Matthew Robson, Sri Chaudhuri, Nicole Riddell, Robert McCrindle, Brock Chittim, Robert Parette, Un-Ho Jin, Stephen Safe, David Poirier, Ralph Ruffolo, Richard Dyer, Rachael Fletcher, Paul A. Helm, Eric J. Reiner
Published 2016-09-01

Natural Products in the Prevention of Metabolic Diseases: Lessons Learned from the 20th KAST Frontier Scientists Workshop

by Seung J. Baek, Bruce D. Hammock, In-Koo Hwang, Qingxiao Li, Naima Moustaid-Moussa, Yeonhwa Park, Stephen Safe, Nanjoo Suh, Sun-Shin Yi, Darryl C. Zeldin, Qixin Zhong, Jennifer Alyce Bradbury, Matthew L. Edin, Joan P. Graves, Hyo-Young Jung, Young-Hyun Jung, Mi-Bo Kim, Woosuk Kim, Jaehak Lee, Hong Li, Jong-Seok Moon, Ik-Dong Yoo, Yiren Yue, Ji-Young Lee, Ho-Jae Han
Published 2021-05-01

1,1-bis(3-indolyl)-1-(p-substitutedphenyl) methanes induce apoptosis and inhibit renal cell carcinoma growth

by York, Melissa Dawn
Published 2010