High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation

by Mohammad Ameen Al-Aghbar, Mohammad Ameen Al-Aghbar, Mohammad Ameen Al-Aghbar, Yeh-Shiu Chu, Bing-Mae Chen, Steve R. Roffler, Steve R. Roffler
Published 2018-04-01

Flow cytometry analysis of anti-polyethylene glycol antibodies in human plasma

by Jia-Long Fang, Frederick A. Beland, Yangshun Tang, Steve R. Roffler
Published 2021-01-01

Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity.

by Yuan-Ting Hsieh, Hsuan-Pei Lin, Bing-Mae Chen, Ping-Ting Huang, Steve R Roffler
Published 2015-01-01

Reversible glycosidic switch for secure delivery of molecular nanocargos

by Pierre-Alain Burnouf, Yu-Lin Leu, Yu-Cheng Su, Kenneth Wu, Wei-Chi Lin, Steve R. Roffler
Published 2018-05-01

Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

by Yu-Cheng Su, Pierre-Alain Burnouf, Kuo-Hsiang Chuang, Bing-Mae Chen, Tian-Lu Cheng, Steve R. Roffler
Published 2017-06-01

Impediments to enhancement of CPT-11 anticancer activity by E. coli directed beta-glucuronidase therapy.

by Yuan-Ting Hsieh, Kai-Chuan Chen, Chiu-Min Cheng, Tian-Lu Cheng, Mi-Hua Tao, Steve R Roffler
Published 2015-01-01

PEGylated Liposomal Methyl Prednisolone Succinate does not Induce Infusion Reactions in Patients: A Correlation Between in Vitro Immunological and in Vivo Clinical Studies

by Yaelle Bavli, Bing-Mae Chen, Steve R. Roffler, Marina A. Dobrovolskaia, Eldad Elnekave, Shifra Ash, Yechezkel Barenholz, Keren Turjeman
Published 2020-01-01

Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

by Sander A. A. Kooijmans, Clara Gómez Aleza, Steve R. Roffler, Wouter W. van Solinge, Pieter Vader, Raymond M. Schiffelers
Published 2016-03-01

CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes

by Thorsten Jung, Donatello Castellana, Pamela Klingbeil, Ines Cuesta Hernández, Mario Vitacolonna, David J. Orlicky, Steve R. Roffler, Pnina Brodt, Margot Zöller
Published 2009-10-01

Structural basis of polyethylene glycol recognition by antibody

by Cheng-Chung Lee, Yu-Cheng Su, Tzu-Ping Ko, Li-Ling Lin, Chih-Ya Yang, Stanley Shi-Chung Chang, Steve R. Roffler, Andrew H.-J. Wang
Published 2020-01-01

The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering

by Bing-Mae Chen, Mohammad Ameen Al-Aghbar, Mohammad Ameen Al-Aghbar, Mohammad Ameen Al-Aghbar, Chien-Hsin Lee, Tien-Ching Chang, Tien-Ching Chang, Tien-Ching Chang, Yu-Cheng Su, Ya-Chen Li, Shih-En Chang, Chin-Chuan Chen, Tsai-Hua Chung, Yuan-Chun Liao, Chau-Hwang Lee, Chau-Hwang Lee, Chau-Hwang Lee, Steve R. Roffler, Steve R. Roffler
Published 2017-07-01

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

by Chia-Jung Chang, Chien-Hsiun Chen, Bing-Mae Chen, Yu-Cheng Su, Ying-Ting Chen, Michael S. Hershfield, Ming-Ta Michael Lee, Tian-Lu Cheng, Yuan-Tsong Chen, Steve R. Roffler, Jer-Yuarn Wu
Published 2017-09-01

The B7-1 cytoplasmic tail enhances intracellular transport and mammalian cell surface display of chimeric proteins in the absence of a linear ER export motif.

by Yi-Chieh Lin, Bing-Mae Chen, Wei-Cheng Lu, Chien-I Su, Zeljko M Prijovich, Wen-Chuan Chung, Pei-Yu Wu, Kai-Chuan Chen, I-Chiao Lee, Ting-Yi Juan, Steve R Roffler
Published 2013-01-01

High-throughput sorting of the highest producing cell via a transiently protein-anchored system.

by Kuo-Hsiang Chuang, Yuan-Chin Hsieh, I-Shiuan Chiang, Chih-Hung Chuang, Chien-Han Kao, Ta-Chun Cheng, Yeng-Tseng Wang, Wen-Wei Lin, Bing-Mae Chen, Steve R Roffler, Ming-Yii Huang, Tian-Lu Cheng
Published 2014-01-01

Discovery of Specific Inhibitors for Intestinal E. coli  β-Glucuronidase through In Silico Virtual Screening

by Ta-Chun Cheng, Kuo-Hsiang Chuang, Steve R. Roffler, Kai-Wen Cheng, Yu-Lin Leu, Chih-Hung Chuang, Chien-Chaio Huang, Chien-Han Kao, Yuan-Chin Hsieh, Long-Sen Chang, Tian-Lu Cheng, Chien-Shu Chen
Published 2015-01-01

A Secondary Antibody-Detecting Molecular Weight Marker with Mouse and Rabbit IgG Fc Linear Epitopes for Western Blot Analysis.

by Wen-Wei Lin, I-Ju Chen, Ta-Chun Cheng, Yi-Ching Tung, Pei-Yu Chu, Chih-Hung Chuang, Yuan-Chin Hsieh, Chien-Chiao Huang, Yeng-Tseng Wang, Chien-Han Kao, Steve R Roffler, Tian-Lu Cheng
Published 2016-01-01

Entropy-driven binding of gut bacterial β-glucuronidase inhibitors ameliorates irinotecan-induced toxicity

by Hsien-Ya Lin, Chia-Yu Chen, Ting-Chien Lin, Lun-Fu Yeh, Wei-Che Hsieh, Shijay Gao, Pierre-Alain Burnouf, Bing-Mae Chen, Tung-Ju Hsieh, Punsaldulam Dashnyam, Yen-Hsi Kuo, Zhijay Tu, Steve R. Roffler, Chun-Hung Lin
Published 2021-03-01

Anti-EphA2 Antibodies Decrease EphA2 Protein Levels in Murine CT26 Colorectal and Human MDA-231 Breast Tumors But Do Not Inhibit Tumor Growth

by David Kiewlich, Jianhuan Zhang, Cynthia Gross, Wei Xia, Brent Larsen, Ronald R. Cobb, Sandra Biroc, Jian-Ming Gu, Takashi Sato, David R. Light, Tara Heitner, Joerg Willuda, David Vogel, Felipe Monteclaro, Andrzej Citkowicz, Steve R. Roffler, Deborah A. Zajchowski
Published 2006-01-01

Double attack strategy for leukemia using a pre-targeting bispecific antibody (CD20 Ab-mPEG scFv) and actively attracting PEGylated liposomal doxorubicin to enhance anti-tumor acti...

by Kai-Wen Ho, I.-J.u Chen, Yi-An Cheng, Tzu-Yi Liao, En-Shuo Liu, Huei-Jen Chen, Yun-Chi Lu, Yu-Cheng Su, Steve R. Roffler, Bo-Cheng Huang, Hui-Ju Liu, Ming-Yii Huang, Chiao-Yun Chen, Tian-Lu Cheng
Published 2021-01-01

Optimization of AID somatic hypermutations system and in situ class switching of Globo H antibodies

by Talal Al-Qaisi, 安奎道
Published 2018