Endoproteolytic cleavage as a molecular switch regulating and diversifying prion protein function

by Cathryn L Haigh, Steven J Collins
Published 2016-01-01

Antioxidant and Metal Chelation-Based Therapies in the Treatment of Prion Disease

by Marcus W. Brazier, Anthony G. Wedd, Steven J. Collins
Published 2014-04-01

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection

by Layla Sinclair, Victoria Lewis, Steven J. Collins, Cathryn L. Haigh
Published 2013-07-01

The Prion Protein N1 and N2 Cleavage Fragments Bind to Phosphatidylserine and Phosphatidic Acid; Relevance to Stress-Protection Responses.

by Cathryn L Haigh, Carolin Tumpach, Simon C Drew, Steven J Collins
Published 2015-01-01

Cellular prion protein expression is not regulated by the Alzheimer's amyloid precursor protein intracellular domain.

by Victoria Lewis, Isobel J Whitehouse, Herbert Baybutt, Jean C Manson, Steven J Collins, Nigel M Hooper
Published 2012-01-01

Extended period of asymptomatic prion disease after low dose inoculation: Assessment of detection methods and implications for infection control

by Steven J. Collins, Victoria Lewis, Marcus W Brazier, Andrew F. Hill, Victoria A. Lawson, Genevieve M. Klug, Colin L. Masters
Published 2005-11-01

Sublethal Concentrations of Prion Peptide PrP106–126 or the Amyloid Beta Peptide of Alzheimer's Disease Activates Expression of Proapoptotic Markers in Primary Cortical Neurons

by Anthony R. White, Ronald Guirguis, Marcus W. Brazier, Michael F. Jobling, Andrew F. Hill, Konrad Beyreuther, Colin J. Barrow, Colin L. Masters, Steven J. Collins, Roberto Cappai
Published 2001-04-01

Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein.

by Victoria A Lawson, Brooke Lumicisi, Jeremy Welton, Dorothy Machalek, Katrina Gouramanis, Helen M Klemm, James D Stewart, Colin L Masters, David E Hoke, Steven J Collins, Andrew F Hill
Published 2010-08-01

Loss of maternal CTCF is associated with peri-implantation lethality of Ctcf null embryos.

by James M Moore, Natalia A Rabaia, Leslie E Smith, Sara Fagerlie, Kay Gurley, Dmitry Loukinov, Christine M Disteche, Steven J Collins, Christopher J Kemp, Victor V Lobanenkov, Galina N Filippova
Published 2012-01-01

Core Alzheimer’s disease cerebrospinal fluid biomarker assays are not affected by aspiration or gravity drip extraction methods

by James D. Doecke, Cindy Francois, Christopher J. Fowler, Erik Stoops, Pierrick Bourgeat, Stephanie R. Rainey-Smith, Qiao-Xin Li, Colin L. Masters, Ralph N. Martins, Victor L. Villemagne, Steven J. Collins, Hugo Marcel Vanderstichele
Published 2021-04-01

Characterization of Prion Disease Associated with a Two-Octapeptide Repeat Insertion

by Nicholas Brennecke, Ignazio Cali, Tze How Mok, Helen Speedy, Genomics England Research Consortium, Laszlo L. P. Hosszu, Christiane Stehmann, Laura Cracco, Gianfranco Puoti, Thomas W. Prior, Mark L. Cohen, Steven J. Collins, Simon Mead, Brian S. Appleby
Published 2021-09-01

Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease

by Franc Llorens, Anna Villar-Piqué, Peter Hermann, Matthias Schmitz, Olga Calero, Christiane Stehmann, Shannon Sarros, Fabio Moda, Isidre Ferrer, Anna Poleggi, Maurizio Pocchiari, Marcella Catania, Sigrid Klotz, Carl O’Regan, Francesca Brett, Josephine Heffernan, Anna Ladogana, Steven J. Collins, Miguel Calero, Gabor G. Kovacs, Inga Zerr
Published 2020-02-01

Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease

by Sonia M. Vallabh, Eric Vallabh Minikel, Victoria J. Williams, Becky C. Carlyle, Alison J. McManus, Chase D. Wennick, Anna Bolling, Bianca A. Trombetta, David Urick, Chloe K. Nobuhara, Jessica Gerber, Holly Duddy, Ingolf Lachmann, Christiane Stehmann, Steven J. Collins, Kaj Blennow, Henrik Zetterberg, Steven E. Arnold
Published 2020-06-01

Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study

by Ignazio Cali, Mark L. Cohen, Stéphane Haїk, Piero Parchi, Giorgio Giaccone, Steven J. Collins, Diane Kofskey, Han Wang, Catriona A. McLean, Jean-Philippe Brandel, Nicolas Privat, Véronique Sazdovitch, Charles Duyckaerts, Tetsuyuki Kitamoto, Ermias D. Belay, Ryan A. Maddox, Fabrizio Tagliavini, Maurizio Pocchiari, Ellen Leschek, Brian S. Appleby, Jiri G. Safar, Lawrence B. Schonberger, Pierluigi Gambetti
Published 2018-01-01

A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk.

by Pascual Sanchez-Juan, Matthew T Bishop, Gabor G Kovacs, Miguel Calero, Yurii S Aulchenko, Anna Ladogana, Alison Boyd, Victoria Lewis, Claudia Ponto, Olga Calero, Anna Poleggi, Ángel Carracedo, Sven J van der Lee, Thomas Ströbel, Fernando Rivadeneira, Albert Hofman, Stéphane Haïk, Onofre Combarros, José Berciano, Andre G Uitterlinden, Steven J Collins, Herbert Budka, Jean-Philippe Brandel, Jean Louis Laplanche, Maurizio Pocchiari, Inga Zerr, Richard S G Knight, Robert G Will, Cornelia M van Duijn
Published 2014-01-01