Molecular profiles to biology and pathways: a systems biology approach

by Steven Van Laere, Luc Dirix, Peter Vermeulen
Published 2016-06-01

A phase I dose-escalation trial of stereotactic ablative body radiotherapy for non-spine bone and lymph node metastases (DESTROY-trial)

by Carole Mercier, Piet Dirix, Paul Meijnders, Peter Vermeulen, Steven Van Laere, Hilde Debois, Philippe Huget, Dirk Verellen
Published 2018-08-01

8q24 Cancer risk allele associated with major metastatic risk in inflammatory breast cancer.

by François Bertucci, Arnaud Lagarde, Anthony Ferrari, Pascal Finetti, Emmanuelle Charafe-Jauffret, Steven Van Laere, José Adelaide, Patrice Viens, Gilles Thomas, Daniel Birnbaum, Sylviane Olschwang
Published 2012-01-01

Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer

by Jonas Steenbrugge, Koen Breyne, Kristel Demeyere, Olivier De Wever, Niek N. Sanders, Wim Van Den Broeck, Cecile Colpaert, Peter Vermeulen, Steven Van Laere, Evelyne Meyer
Published 2018-08-01

Expression of X-Linked Inhibitor of Apoptosis Protein (XIAP) in Breast Cancer Is Associated with Shorter Survival and Resistance to Chemotherapy

by Gayathri R. Devi, Pascal Finetti, Michael A. Morse, Seayoung Lee, Alexandre de Nonneville, Steven Van Laere, Jesse Troy, Joseph Geradts, Shannon McCall, Francois Bertucci
Published 2021-06-01

Outcome and toxicity of hypofractionated image-guided SABR for spinal oligometastases

by Charlotte Billiet, Ines Joye, Carole Mercier, Lieselotte Depuydt, Geert De Kerf, Peter Vermeulen, Steven Van Laere, Erik Van de Kelft, Paul Meijnders, Dirk Verellen, Piet Dirix
Published 2020-09-01

Immune landscape of inflammatory breast cancer suggests vulnerability to immune checkpoint inhibitors

by François Bertucci, Laurys Boudin, Pascal Finetti, Christophe Van Berckelaer, Peter Van Dam, Luc Dirix, Patrice Viens, Anthony Gonçalves, Naoto T. Ueno, Steven Van Laere, Daniel Birnbaum, Emilie Mamessier
Published 2021-01-01

HER-2 status of circulating tumor cells in a metastatic breast cancer cohort: A comparative study on characterization techniques.

by Anja Brouwer, Bram De Laere, Pieter-Jan van Dam, Dieter Peeters, Jasper Van Haver, Ellen Sluydts, Ali El Moussaoui, Pauline Mendelaar, Jaco Kraan, Marc Peeters, Steven Van Laere, Luc Dirix
Published 2019-01-01

Characterization and Targeting of Platelet-Derived Growth Factor Receptor alpha (PDGFRA) in Inflammatory Breast Cancer (IBC)

by Madhura Joglekar-Javadekar, Steven Van Laere, Michael Bourne, Manal Moalwi, Pascal Finetti, Peter B. Vermeulen, Daniel Birnbaum, Luc Y. Dirix, Naoto Ueno, Monique Carter, Justin Rains, Abhijit Ramachandran, Francois Bertucci, Kenneth L. van Golen
Published 2017-07-01

The Evolution and Prognostic Role of Tumour-Infiltrating Lymphocytes and Peripheral Blood-Based Biomarkers in Inflammatory Breast Cancer Patients Treated with Neoadjuvant Chemother...

by Christophe Van Berckelaer, Iris Vermeiren, Leonie Vercauteren, Charlotte Rypens, Gizem Oner, Xuan Bich Trinh, Wiebren A. A. Tjalma, Glenn Broeckx, Emmanuelle Charafe-Jauffret, Steven Van Laere, François Bertucci, Cecile Colpaert, Peter A. van Dam
Published 2021-09-01

Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer

by Jonas Steenbrugge, Jonas Steenbrugge, Jonas Steenbrugge, Niels Vander Elst, Kristel Demeyere, Olivier De Wever, Olivier De Wever, Niek N. Sanders, Niek N. Sanders, Wim Van Den Broeck, Luc Dirix, Steven Van Laere, Evelyne Meyer, Evelyne Meyer
Published 2019-12-01

NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non‐inflammatory breast cancers

by François Bertucci, Charlotte Rypens, Pascal Finetti, Arnaud Guille, José Adélaïde, Audrey Monneur, Nadine Carbuccia, Séverine Garnier, Piet Dirix, Anthony Gonçalves, Peter Vermeulen, Bisrat G. Debeb, Xiaoping Wang, Luc Dirix, Naoto T. Ueno, Patrice Viens, Massimo Cristofanilli, Max Chaffanet, Daniel Birnbaum, Steven Van Laere
Published 2020-03-01

Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion

by Emilly S. Villodre, Xiaoding Hu, Richard Larson, Pascal Finetti, Kristen Gomez, Wintana Balema, Shane R. Stecklein, Ginette Santiago‐Sanchez, Savitri Krishnamurthy, Juhee Song, Xiaoping Su, Naoto T. Ueno, Debu Tripathy, Steven Van Laere, François Bertucci, Pablo Vivas‐Mejía, Wendy A. Woodward, Bisrat G. Debeb
Published 2021-10-01

Association between the histopathological growth patterns of liver metastases and survival after hepatic surgery in breast cancer patients

by Ali Bohlok, Peter Vermeulen, Sophia Leduc, Emily Latacz, Lara Botzenhart, François Richard, Maxim De Schepper, Tatjana Geukens, Valerio Lucidi, Michail Ignatiadis, Philippe Aftimos, Christos Sotiriou, Martine Piccart, Alain Hendlisz, Steven Van Laere, Luc Dirix, Jean-Christophe Noël, Elia Biganzoli, Denis Larsimont, Christine Desmedt, Vincent Donckier
Published 2020-12-01

Rates of immune cell infiltration in patients with triple-negative breast cancer by molecular subtype.

by Kenichi Harano, Ying Wang, Bora Lim, Robert S Seitz, Stephan W Morris, Daniel B Bailey, David R Hout, Rachel L Skelton, Brian Z Ring, Hiroko Masuda, Arvind U K Rao, Steven Van Laere, Francois Bertucci, Wendy A Woodward, James M Reuben, Savitri Krishnamurthy, Naoto T Ueno
Published 2018-01-01

Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer

by Marie-Julie Nokin, Justine Bellier, Florence Durieux, Olivier Peulen, Gilles Rademaker, Maude Gabriel, Christine Monseur, Benoit Charloteaux, Lieven Verbeke, Steven van Laere, Patrick Roncarati, Michael Herfs, Charles Lambert, Jean Scheijen, Casper Schalkwijk, Alain Colige, Jo Caers, Philippe Delvenne, Andrei Turtoi, Vincent Castronovo, Akeila Bellahcène
Published 2019-01-01

Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern

by Sébastien Tabariès, Matthew G. Annis, Anthoula Lazaris, Stephanie K. Petrillo, Jennifer Huxham, Amri Abdellatif, Vincent Palmieri, Jaclyn Chabot, Radia M. Johnson, Steven Van Laere, Cornelis Verhoef, Yasmina Hachem, Sara Yumeen, Nicholas Meti, Atilla Omeroglu, Gulbeyaz Altinel, Zu-Hua Gao, Alan S. L. Yu, Dirk J. Grünhagen, Peter Vermeulen, Peter Metrakos, Peter M. Siegel
Published 2021-06-01

Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis

by Markus Mayrhofer, Bram De Laere, Tom Whitington, Peter Van Oyen, Christophe Ghysel, Jozef Ampe, Piet Ost, Wim Demey, Lucien Hoekx, Dirk Schrijvers, Barbara Brouwers, Willem Lybaert, Els Everaert, Daan De Maeseneer, Michiel Strijbos, Alain Bols, Karen Fransis, Steffi Oeyen, Pieter-Jan van Dam, Gert Van den Eynden, Annemie Rutten, Markus Aly, Tobias Nordström, Steven Van Laere, Mattias Rantalainen, Prabhakar Rajan, Lars Egevad, Anders Ullén, Jeffrey Yachnin, Luc Dirix, Henrik Grönberg, Johan Lindberg
Published 2018-11-01

Tumor vessel co-option probed by single-cell analysis

by Laure-Anne Teuwen, Laura P.M.H. De Rooij, Anne Cuypers, Katerina Rohlenova, Sébastien J. Dumas, Melissa García-Caballero, Elda Meta, Jacob Amersfoort, Federico Taverna, Lisa M. Becker, Nuphar Veiga, Anna Rita Cantelmo, Vincent Geldhof, Nadine V. Conchinha, Joanna Kalucka, Lucas Treps, Lena-Christin Conradi, Shawez Khan, Tobias K. Karakach, Stefaan Soenen, Stefan Vinckier, Luc Schoonjans, Guy Eelen, Steven Van Laere, Mieke Dewerchin, Luc Dirix, Massimiliano Mazzone, Yonglun Luo, Peter Vermeulen, Peter Carmeliet
Published 2021-06-01

The topography of mutational processes in breast cancer genomes

by Sandro Morganella, Ludmil B. Alexandrov, Dominik Glodzik, Xueqing Zou, Helen Davies, Johan Staaf, Anieta M. Sieuwerts, Arie B. Brinkman, Sancha Martin, Manasa Ramakrishna, Adam Butler, Hyung-Yong Kim, Åke Borg, Christos Sotiriou, P. Andrew Futreal, Peter J. Campbell, Paul N. Span, Steven Van Laere, Sunil R. Lakhani, Jorunn E. Eyfjord, Alastair M. Thompson, Hendrik G. Stunnenberg, Marc J. van de Vijver, John W. M. Martens, Anne-Lise Børresen-Dale, Andrea L. Richardson, Gu Kong, Gilles Thomas, Julian Sale, Cristina Rada, Michael R. Stratton, Ewan Birney, Serena Nik-Zainal
Published 2016-05-01