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Sue T. Griffin

Wilma Sue Tilton Griffin (born January 25, 1934) is an American neuroscientist best known for her contributions regarding the role of neuroinflammation in the pathogenesis of Alzheimer's disease and other neurodegenerative conditions. She conceived a "cytokine cycle" by which interleukin 1 and other paracrine factors conspire with one another to create a "feed-forward" cooperativity, thus establishing the premise for a progressive disease. Griffin is the Alexa and William T. Dillard Professor in Geriatric Research and director of research at the Donald W. Reynolds Institute on Aging at the University of Arkansas for Medical Sciences. She is also the founding Chief Editor of the Journal of Neuroinflammation. Provided by Wikipedia

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Multiple metabolic alterations exist in mutant PI3K cancers, but only glucose is essential as a nutrient source.

by Rebecca Foster, Sue Griffin, Suzanne Grooby, Ruth Feltell, Cindy Christopherson, Monica Chang, John Sninsky, Shirley Kwok, Chris Torrance
Published 2012-01-01

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2

Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes.

by Jeffrey J Wallin, Jane Guan, Kyle A Edgar, Wei Zhou, Ross Francis, Anthony C Torres, Peter M Haverty, Jeffrey Eastham-Anderson, Sabrina Arena, Alberto Bardelli, Sue Griffin, John E Goodall, Kyla M Grimshaw, Klaus P Hoeflich, Christopher Torrance, Marcia Belvin, Lori S Friedman
Published 2012-01-01

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