Sue T. Griffin

Wilma Sue Tilton Griffin (born January 25, 1934) is an American neuroscientist best known for her contributions regarding the role of neuroinflammation in the pathogenesis of Alzheimer's disease and other neurodegenerative conditions. She conceived a "cytokine cycle" by which interleukin 1 and other paracrine factors conspire with one another to create a "feed-forward" cooperativity, thus establishing the premise for a progressive disease. Griffin is the Alexa and William T. Dillard Professor in Geriatric Research and director of research at the Donald W. Reynolds Institute on Aging at the University of Arkansas for Medical Sciences. She is also the founding Chief Editor of the Journal of Neuroinflammation. Provided by Wikipedia
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    Aging, Alzheimer’s, and APOE genotype influence the expression and neuronal distribution patterns of microtubule motor protein dynactin-P50
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    Aggregate Interactome Based on Protein Cross-linking Interfaces Predicts Drug Targets to Limit Aggregation in Neurodegenerative Diseases
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    A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer’s Disease
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    Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site
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