HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking

by Mariana Marin, Yulia Kushnareva, Caleb S. Mason, Sumit K. Chanda, Gregory B. Melikyan
Published 2019-01-01

Sensor Sensibility—HIV-1 and the Innate Immune Response

by Xin Yin, Simon Langer, Zeli Zhang, Kristina M. Herbert, Sunnie Yoh, Renate König, Sumit K. Chanda
Published 2020-01-01

In silico gene prioritization by integrating multiple data sources.

by Yixuan Chen, Wenhui Wang, Yingyao Zhou, Robert Shields, Sumit K Chanda, Robert C Elston, Jing Li
Published 2011-01-01

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

by Yingyao Zhou, Bin Zhou, Lars Pache, Max Chang, Alireza Hadj Khodabakhshi, Olga Tanaseichuk, Christopher Benner, Sumit K. Chanda
Published 2019-04-01

A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a.

by Jeffrey T Irelan, Ana Gutierrez Del Arroyo, Abel Gutierrez, Gordon Peters, Kim C Quon, Loren Miraglia, Sumit K Chanda
Published 2009-01-01

An integrated map of HIV-human protein complexes that facilitate viral infection.

by Dorothea Emig-Agius, Kevin Olivieri, Lars Pache, Hsin Ling Shih, Olga Pustovalova, Marina Bessarabova, John A T Young, Sumit K Chanda, Trey Ideker
Published 2014-01-01

Identification of Polo-like kinases as potential novel drug targets for influenza A virus

by Marie O. Pohl, Jessica von Recum-Knepper, Ariel Rodriguez-Frandsen, Caroline Lanz, Emilio Yángüez, Stephen Soonthornvacharin, Thorsten Wolff, Sumit K. Chanda, Silke Stertz
Published 2017-08-01

Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling.

by Wei Li, Mario H Bengtson, Axel Ulbrich, Akio Matsuda, Venkateshwar A Reddy, Anthony Orth, Sumit K Chanda, Serge Batalov, Claudio A P Joazeiro
Published 2008-01-01

Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu

by Prashant Jain, Guney Boso, Simon Langer, Stephen Soonthornvacharin, Paul D. De Jesus, Quy Nguyen, Kevin C. Olivieri, Alex J. Portillo, Sunnie M. Yoh, Lars Pache, Sumit K. Chanda
Published 2018-02-01

The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription

by Simon Langer, Xin Yin, Arturo Diaz, Alex J. Portillo, David E. Gordon, Umu H. Rogers, John M. Marlett, Nevan J. Krogan, John A. T. Young, Lars Pache, Sumit K. Chanda
Published 2020-09-01

Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus.

by Fuqu Yu, Josephine N Harada, Helen J Brown, Hongyu Deng, Moon Jung Song, Ting-Ting Wu, Juran Kato-Stankiewicz, Christian G Nelson, Jeffrey Vieira, Fuyuhiko Tamanoi, Sumit K Chanda, Ren Sun
Published 2007-03-01

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses

by Simon Langer, Christian Hammer, Kristina Hopfensperger, Lukas Klein, Dominik Hotter, Paul D De Jesus, Kristina M Herbert, Lars Pache, Nikaïa Smith, Johannes A van der Merwe, Sumit K Chanda, Jacques Fellay, Frank Kirchhoff, Daniel Sauter
Published 2019-02-01

HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.

by Karen E Ocwieja, Troy L Brady, Keshet Ronen, Alyssa Huegel, Shoshannah L Roth, Torsten Schaller, Leo C James, Greg J Towers, John A T Young, Sumit K Chanda, Renate König, Nirav Malani, Charles C Berry, Frederic D Bushman
Published 2011-03-01

Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo

by Lars Pache, Matthew D. Marsden, Peter Teriete, Alex J. Portillo, Dominik Heimann, Jocelyn T. Kim, Mohamed S.A. Soliman, Melanie Dimapasoc, Camille Carmona, Maria Celeridad, Adam M. Spivak, Vicente Planelles, Nicholas D.P. Cosford, Jerome A. Zack, Sumit K. Chanda
Published 2020-06-01

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

by Xin Yin, Laura Riva, Yuan Pu, Laura Martin-Sancho, Jun Kanamune, Yuki Yamamoto, Kouji Sakai, Shimpei Gotoh, Lisa Miorin, Paul D. De Jesus, Chih-Cheng Yang, Kristina M. Herbert, Sunnie Yoh, Judd F. Hultquist, Adolfo García-Sastre, Sumit K. Chanda
Published 2021-01-01

Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.

by Amanda M Opaluch, Monika Schneider, Chih-yuan Chiang, Quy T Nguyen, Ana M Maestre, Lubbertus C F Mulder, Ismael Secundino, Paul D De Jesus, Renate König, Viviana Simon, Victor Nizet, Graham MacLeod, Susannah Varmuza, Ana Fernandez-Sesma, Sumit K Chanda
Published 2014-01-01

Host cell factors in HIV replication: meta-analysis of genome-wide studies.

by Frederic D Bushman, Nirav Malani, Jason Fernandes, Iván D'Orso, Gerard Cagney, Tracy L Diamond, Honglin Zhou, Daria J Hazuda, Amy S Espeseth, Renate König, Sourav Bandyopadhyay, Trey Ideker, Stephen P Goff, Nevan J Krogan, Alan D Frankel, John A T Young, Sumit K Chanda
Published 2009-05-01