Attrition of T-cell functions and simultaneous upregulation of inhibitory markers correspond with the waning of BCG-induced protection against tuberculosis in mice.

by Subhadra Nandakumar, Sunil Kannanganat, James E Posey, Rama Rao Amara, Suraj B Sable
Published 2014-01-01

Cellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination.

by Suraj B Sable, Mani Cheruvu, Subhadra Nandakumar, Sunita Sharma, Kakali Bandyopadhyay, Kathryn L Kellar, James E Posey, Bonnie B Plikaytis, Rama Rao Amara, Thomas M Shinnick
Published 2011-01-01

O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection.

by Subhadra Nandakumar, Sunil Kannanganat, Karen M Dobos, Megan Lucas, John S Spencer, Sunan Fang, Melissa A McDonald, Jan Pohl, Kristin Birkness, Venkateswarlu Chamcha, Melissa V Ramirez, Bonnie B Plikaytis, James E Posey, Rama Rao Amara, Suraj B Sable
Published 2013-01-01