Peroxisome Proliferator-Activated Receptors in Diabetic Nephropathy

by Shinji Kume, Takashi Uzu, Keiji Isshiki, Daisuke Koya
Published 2008-01-01

Role of Nutrient-Sensing Signals in the Pathogenesis of Diabetic Nephropathy

by Shinji Kume, Daisuke Koya, Takashi Uzu, Hiroshi Maegawa
Published 2014-01-01

The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy

by Kosuke Yamahara, Mako Yasuda, Shinji Kume, Daisuke Koya, Hiroshi Maegawa, Takashi Uzu
Published 2013-01-01

Recurrent pleuroperitoneal leak caused by diaphragm blebs in a peritoneal dialysis patient: a case report with literature review

by Yoshihiko Fujino, Noritaka Kawada, Katsukiyo Ito, Hiroshi Katsura, Hajime Maeda, Kensuke Mitsumoto, Takashi Uzu
Published 2018-10-01

Successful Renal Replacement Therapy for a Patient with Severe Hemophilia after Surgical Treatment of Intracranial Hemorrhage and Hydrocephalus

by Noriko Kato, Masami Chin-Kanasaki, Yuki Tanaka, Mako Yasuda, Yukiyo Yokomaku, Masayoshi Sakaguchi, Keiji Isshiki, Shin-ichi Araki, Shigeru Ohta, Takashi Uzu
Published 2011-01-01

Stearoyl-CoA Desaturase-1 Protects Cells against Lipotoxicity-Mediated Apoptosis in Proximal Tubular Cells

by Tamaki Iwai, Shinji Kume, Masami Chin-Kanasaki, Shogo Kuwagata, Hisazumi Araki, Naoko Takeda, Takeshi Sugaya, Takashi Uzu, Hiroshi Maegawa, Shin-ichi Araki
Published 2016-11-01

The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetes.

by Mahiro Kurashige, Minako Imamura, Shin-Ichi Araki, Daisuke Suzuki, Tetsuya Babazono, Takashi Uzu, Tomoya Umezono, Masao Toyoda, Koichi Kawai, Masahito Imanishi, Kazushige Hanaoka, Hiroshi Maegawa, Yasuko Uchigata, Tatsuo Hosoya, Shiro Maeda
Published 2013-01-01

Predictive properties of plasma amino acid profile for cardiovascular disease in patients with type 2 diabetes.

by Shinji Kume, Shin-ichi Araki, Nobukazu Ono, Atsuko Shinhara, Takahiko Muramatsu, Hisazumi Araki, Keiji Isshiki, Kazuki Nakamura, Hiroshi Miyano, Daisuke Koya, Masakazu Haneda, Satoshi Ugi, Hiromichi Kawai, Atsunori Kashiwagi, Takashi Uzu, Hiroshi Maegawa
Published 2014-01-01

GW501516, a PPARδ agonist, ameliorates tubulointerstitial inflammation in proteinuric kidney disease via inhibition of TAK1-NFκB pathway in mice.

by Xu Yang, Shinji Kume, Yuki Tanaka, Keiji Isshiki, Shin-ichi Araki, Masami Chin-Kanasaki, Toshiro Sugimoto, Daisuke Koya, Masakazu Haneda, Takeshi Sugaya, Detian Li, Ping Han, Yoshihiko Nishio, Atsunori Kashiwagi, Hiroshi Maegawa, Takashi Uzu
Published 2011-01-01

4-Hydroxy hexenal derived from docosahexaenoic acid protects endothelial cells via Nrf2 activation.

by Atsushi Ishikado, Katsutaro Morino, Yoshihiko Nishio, Fumiyuki Nakagawa, Atsushi Mukose, Yoko Sono, Nagisa Yoshioka, Keiko Kondo, Osamu Sekine, Takeshi Yoshizaki, Satoshi Ugi, Takashi Uzu, Hiromichi Kawai, Taketoshi Makino, Tomio Okamura, Masayuki Yamamoto, Atsunori Kashiwagi, Hiroshi Maegawa
Published 2013-01-01

Hypothalamic AMP-Activated Protein Kinase Regulates Biphasic Insulin Secretion from Pancreatic β Cells during Fasting and in Type 2 Diabetes

by Shinji Kume, Motoyuki Kondo, Shiro Maeda, Yoshihiko Nishio, Tsuyoshi Yanagimachi, Yukihiro Fujita, Masakazu Haneda, Keiko Kondo, Akihiro Sekine, Shin-ich Araki, Hisazumi Araki, Masami Chin-Kanasaki, Satoshi Ugi, Daisuke Koya, Sawako Kitahara, Kiyosumi Maeda, Atsunori Kashiwagi, Takashi Uzu, Hiroshi Maegawa
Published 2016-11-01

Randomized trial of an intensified, multifactorial intervention in patients with advanced‐stage diabetic kidney disease: Diabetic Nephropathy Remission and Regression Team Trial in...

by Kenichi Shikata, Masakazu Haneda, Toshiharu Ninomiya, Daisuke Koya, Yoshiki Suzuki, Daisuke Suzuki, Hitoshi Ishida, Hiroaki Akai, Yasuhiko Tomino, Takashi Uzu, Motonobu Nishimura, Shiro Maeda, Daisuke Ogawa, Satoshi Miyamoto, Hirofumi Makino, the Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT‐Japan) collaborative group
Published 2021-02-01

Comparative Effects of Direct Renin Inhibitor and Angiotensin Receptor Blocker on Albuminuria in Hypertensive Patients with Type 2 Diabetes. A Randomized Controlled Trial.

by Takashi Uzu, Shin-Ichi Araki, Atsunori Kashiwagi, Masakazu Haneda, Daisuke Koya, Hiroki Yokoyama, Yasuo Kida, Motoyoshi Ikebuchi, Takaaki Nakamura, Masataka Nishimura, Noriko Takahara, Toshiyuki Obata, Nobuyuki Omichi, Katsuhiko Sakamoto, Ryosuke Shingu, Hideki Taki, Yoshio Nagai, Hiroaki Tokuda, Munehiro Kitada, Miwa Misawa, Akira Nishiyama, Hiroyuki Kobori, Hiroshi Maegawa, Shiga Committee for Preventing Diabetic Nephropathy
Published 2016-01-01

An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.

by Lijun Ma, Mariana Murea, James A Snipes, Alejandra Marinelarena, Jacqueline Krüger, Pamela J Hicks, Kurt A Langberg, Meredith A Bostrom, Jessica N Cooke, Daisuke Suzuki, Tetsuya Babazono, Takashi Uzu, Sydney C W Tang, Ashis K Mondal, Neeraj K Sharma, Sayuko Kobes, Peter A Antinozzi, Matthew Davis, Swapan K Das, Neda Rasouli, Philip A Kern, Nathan J Shores, Lawrence L Rudel, Matthias Blüher, Michael Stumvoll, Donald W Bowden, Shiro Maeda, John S Parks, Peter Kovacs, Robert L Hanson, Leslie J Baier, Steven C Elbein, Barry I Freedman
Published 2013-01-01