A novel system for transcutaneous application of carbon dioxide causing an "artificial Bohr effect" in the human body.

by Yoshitada Sakai, Masahiko Miwa, Keisuke Oe, Takeshi Ueha, Akihiro Koh, Takahiro Niikura, Takashi Iwakura, Sang Yang Lee, Masaya Tanaka, Masahiro Kurosaka
Published 2011-01-01

P21 deficiency delays regeneration of skeletal muscular tissue.

by Nobuaki Chinzei, Shinya Hayashi, Takeshi Ueha, Takaaki Fujishiro, Noriyuki Kanzaki, Shingo Hashimoto, Shuhei Sakata, Shinsuke Kihara, Masahiko Haneda, Yoshitada Sakai, Ryosuke Kuroda, Masahiro Kurosaka
Published 2015-01-01

Transcutaneous application of carbon dioxide (CO2) induces mitochondrial apoptosis in human malignant fibrous histiocytoma in vivo.

by Yasuo Onishi, Teruya Kawamoto, Takeshi Ueha, Kenta Kishimoto, Hitomi Hara, Naomasa Fukase, Mitsunori Toda, Risa Harada, Masaya Minoda, Yoshitada Sakai, Masahiko Miwa, Masahiro Kurosaka, Toshihiro Akisue
Published 2012-01-01

Methotrexate upregulates circadian transcriptional factors PAR bZIP to induce apoptosis on rheumatoid arthritis synovial fibroblasts

by Kohjin Suzuki, Kohsuke Yoshida, Takeshi Ueha, Kenta Kaneshiro, Ayako Nakai, Naonori Hashimoto, Koto Uchida, Teppei Hashimoto, Yoshiko Kawasaki, Nao Shibanuma, Natsuko Nakagawa, Yoshitada Sakai, Akira Hashiramoto
Published 2018-03-01

Transcutaneous carbon dioxide induces mitochondrial apoptosis and suppresses metastasis of oral squamous cell carcinoma in vivo.

by Daisuke Takeda, Takumi Hasegawa, Takeshi Ueha, Yusuke Imai, Akiko Sakakibara, Masaya Minoda, Teruya Kawamoto, Tsutomu Minamikawa, Yasuyuki Shibuya, Toshihiro Akisue, Yoshitada Sakai, Masahiro Kurosaka, Takahide Komori
Published 2014-01-01