Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation

by Akihiro Sugai, Taisuke Kato, Akihide Koyama, Yuka Koike, Takuya Konno, Tomohiko Ishihara, Osamu Onodera
Published 2019-10-01

Robustness and Vulnerability of the Autoregulatory System That Maintains Nuclear TDP-43 Levels: A Trade-off Hypothesis for ALS Pathology Based on in Silico Data

by Akihiro Sugai, Taisuke Kato, Akihide Koyama, Yuka Koike, Sou Kasahara, Takuya Konno, Tomohiko Ishihara, Osamu Onodera
Published 2018-02-01

A patient clinically diagnosed as multiple system atrophy harboring LRRK2 p.G2019S

by Shoichiro Ando, Takuya Konno, Tomohiko Ishihara, Hideki Hayashi, Natsumi Saito, Kenya Nishioka, Nobutaka Hattori, Zbigniew K. Wszolek, Osamu Onodera
Published 2019-01-01

Association of MAPT subhaplotypes with clinical and demographic features in Parkinson’s disease

by Angela B. Deutschlander, Takuya Konno, Alexandra I. Soto‐Beasley, Ronald L. Walton, Jay A. vanGerpen, Ryan J. Uitti, Michael G. Heckman, Zbigniew K. Wszolek, Owen A. Ross
Published 2020-09-01