Polymer Modeling Predicts Chromosome Reorganization in Senescence

by Michael Chiang, Davide Michieletto, Chris A. Brackley, Nattaphong Rattanavirotkul, Hisham Mohammed, Davide Marenduzzo, Tamir Chandra
Published 2019-09-01

A Stem Cell Reporter for Investigating Pluripotency and Self-Renewal in the Rat

by Stephen Meek, Jun Wei, Taeho Oh, Tom Watson, Jaime Olavarrieta, Linda Sutherland, Daniel F. Carlson, Angela Salzano, Tamir Chandra, Anagha Joshi, Tom Burdon
Published 2020-01-01

Global Reorganization of the Nuclear Landscape in Senescent Cells

by Tamir Chandra, Philip Andrew Ewels, Stefan Schoenfelder, Mayra Furlan-Magaril, Steven William Wingett, Kristina Kirschner, Jean-Yves Thuret, Simon Andrews, Peter Fraser, Wolf Reik
Published 2015-02-01

Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

by Hisham Mohammed, Irene Hernando-Herraez, Aurora Savino, Antonio Scialdone, Iain Macaulay, Carla Mulas, Tamir Chandra, Thierry Voet, Wendy Dean, Jennifer Nichols, John C. Marioni, Wolf Reik
Published 2017-08-01

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment

by Kristina Kirschner, Tamir Chandra, Vladimir Kiselev, David Flores-Santa Cruz, Iain C. Macaulay, Hyun Jun Park, Juan Li, David G. Kent, Rupa Kumar, Dean C. Pask, Tina L. Hamilton, Martin Hemberg, Wolf Reik, Anthony R. Green
Published 2017-05-01

Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.

by Kristina Kirschner, Shamith A Samarajiwa, Jonathan M Cairns, Suraj Menon, Pedro A Pérez-Mancera, Kosuke Tomimatsu, Camino Bermejo-Rodriguez, Yoko Ito, Tamir Chandra, Masako Narita, Scott K Lyons, Andy G Lynch, Hiroshi Kimura, Tetsuya Ohbayashi, Simon Tavaré, Masashi Narita
Published 2015-03-01

Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair

by Juan Carlos Lopez-Baez, Daniel J Simpson, Laura LLeras Forero, Zhiqiang Zeng, Hannah Brunsdon, Angela Salzano, Alessandro Brombin, Cameron Wyatt, Witold Rybski, Leonie F A Huitema, Rodney M Dale, Koichi Kawakami, Christoph Englert, Tamir Chandra, Stefan Schulte-Merker, Nicholas D Hastie, E Elizabeth Patton
Published 2018-02-01

An epigenome-wide association study of sex-specific chronological ageing

by Daniel L. McCartney, Futao Zhang, Robert F. Hillary, Qian Zhang, Anna J. Stevenson, Rosie M. Walker, Mairead L. Bermingham, Thibaud Boutin, Stewart W. Morris, Archie Campbell, Alison D. Murray, Heather C. Whalley, David J. Porteous, Caroline Hayward, Kathryn L. Evans, Tamir Chandra, Ian J. Deary, Andrew M. McIntosh, Jian Yang, Peter M. Visscher, Allan F. McRae, Riccardo E. Marioni
Published 2019-12-01