Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

by Xionghao Lin, Xionghao Lin, Tatiana Ammosova, Tatiana Ammosova, Tatiana Ammosova, Meng S. Choy, Colette A. Pietzsch, Andrey Ivanov, Asrar Ahmad, Yasemin Saygideğer, Namita Kumari, Dmytro Kovalskyy, Aykut Üren, Wolfgang Peti, Alexander Bukreyev, Sergei Nekhai, Sergei Nekhai
Published 2019-09-01

Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175.

by Tatiana Ammosova, Yuri Obukhov, Alexander Kotelkin, Denitra Breuer, Monique Beullens, Victor R Gordeuk, Mathieu Bollen, Sergei Nekhai
Published 2011-04-01

Protein Phosphatase-1 Regulates Expression of Neuregulin-1

by Tatiana Ammosova, Kareem Washington, Jamie Rotimi, Namita Kumari, Kahli A. Smith, Xiaomei Niu, Marina Jerebtsova, Sergei Nekhai
Published 2016-12-01

Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.

by Tatiana Ammosova, Maxim Platonov, Venkat R K Yedavalli, Yuri Obukhov, Victor R Gordeuk, Kuan-Teh Jeang, Dmytro Kovalskyy, Sergei Nekhai
Published 2012-01-01

HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription

by Andrey Ivanov, Xionghao Lin, Tatiana Ammosova, Andrey V. Ilatovskiy, Namita Kumari, Hatajai Lassiter, Nowah Afangbedji, Xiaomei Niu, Michael G. Petukhov, Sergei Nekhai
Published 2018-05-01

Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection.

by Patrick Younan, Rodrigo I Santos, Palaniappan Ramanathan, Mathieu Iampietro, Andrew Nishida, Mukta Dutta, Tatiana Ammosova, Michelle Meyer, Michael G Katze, Vsevolod L Popov, Sergei Nekhai, Alexander Bukreyev
Published 2019-10-01