Isotropic 25-Micron 3D Neuroimaging Using ex vivo Microstructural Manganese-Enhanced MRI (MEMRI)

by Chika Sato, Chika Sato, Kazuhiko Sawada, David Wright, David Wright, Tatsuya Higashi, Tatsuya Higashi, Ichio Aoki, Ichio Aoki
Published 2018-12-01

New potential biomarker for stratification of patients for pharmacological vitamin C in adjuvant settings of cancer therapy

by Rumiana Bakalova, Zhivko Zhelev, Thomas Miller, Ichio Aoki, Tatsuya Higashi
Published 2020-01-01

Vitamin C versus Cancer: Ascorbic Acid Radical and Impairment of Mitochondrial Respiration?

by Rumiana Bakalova, Zhivko Zhelev, Thomas Miller, Ichio Aoki, Tatsuya Higashi
Published 2020-01-01

Misery perfusion and amyloid deposition in atherosclerotic major cerebral artery disease

by Hiroshi Yamauchi, Shinya Kagawa, Masaaki Takahashi, Naoya Oishi, Masahiro Ono, Tatsuya Higashi
Published 2019-01-01

Proof of Concept Study for Increasing Tenascin-C-Targeted Drug Delivery to Tumors Previously Subjected to Therapy: X-Irradiation Increases Tumor Uptake

by Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Kanako Takano, Moriaki Kusakabe, Tatsuya Higashi
Published 2020-12-01

Quantitative Radionuclide Imaging Analysis of Enhanced Drug Delivery Induced by Photoimmunotherapy

by Winn Aung, Atsushi B. Tsuji, Aya Sugyo, Masayuki Fujinaga, Ming-Rong Zhang, Tatsuya Higashi
Published 2021-08-01

Vitamin K: Redox-modulation, prevention of mitochondrial dysfunction and anticancer effect

by Donika Ivanova, Zhivko Zhelev, Plamen Getsov, Biliana Nikolova, Ichio Aoki, Tatsuya Higashi, Rumiana Bakalova
Published 2018-06-01

Benzothiazepines, diltiazem and JTV-519, exert an anxiolytic-like effect via neurosteroid biosynthesis in mice

by Kazumi Yoshizawa, Kozue Nakashima, Mizuho Tabuchi, Ayano Okumura, Yuko Nakatake, Mitsuhiko Yamada, Yayoi Tsuneoka, Tatsuya Higashi
Published 2020-07-01

“Redox Imaging” to Distinguish Cells with Different Proliferative Indexes: Superoxide, Hydroperoxides, and Their Ratio as Potential Biomarkers

by Zhivko Zhelev, Ekaterina Georgieva, Dessislava Lazarova, Severina Semkova, Ichio Aoki, Maya Gulubova, Tatsuya Higashi, Rumiana Bakalova
Published 2019-01-01

Formation of cholesterol ozonolysis products in vitro and in vivo through a myeloperoxidase-dependent pathway

by Susumu Tomono, Noriyuki Miyoshi, Hidemi Shiokawa, Tomoe Iwabuchi, Yasuaki Aratani, Tatsuya Higashi, Haruo Nukaya, Hiroshi Ohshima
Published 2011-01-01

Longitudinal stability of a multimodal visco-elastic polyacrylamide gel phantom for magnetic resonance and ultrasound shear-wave elastography.

by Masashi Usumura, Riwa Kishimoto, Koki Ishii, Eika Hotta, Jeff Kershaw, Tatsuya Higashi, Takayuki Obata, Mikio Suga
Published 2021-01-01

Establishment of an In Vivo Xenograft Mouse Model of a Subcutaneous Submillimeter HT-29 Tumor Formed from a Single Spheroid Transplanted Using Radiation-Crosslinked Gelatin Hydroge...

by Tomoko Tachibana, Tomoko Gowa Oyama, Yukie Yoshii, Fukiko Hihara, Chika Igarashi, Atsushi B Tsuji, Tatsuya Higashi, Mitsumasa Taguchi
Published 2021-07-01

Single-Dose Cisplatin Pre-Treatment Enhances Efficacy of ROBO1-Targeted Radioimmunotherapy

by Kentaro Fujiwara, Keitaro Koyama, Atsushi B. Tsuji, Hiroko Iwanari, Osamu Kusano-Arai, Tatsuya Higashi, Toshimitsu Momose, Takao Hamakubo
Published 2020-10-01

Differential Uptake of 18F-fluorodeoxyglucose by Experimental Tumors Xenografted into Immunocompetent and Immunodeficient Mice and the Effect of Immunomodification

by Marcelo Mamede, Tsuneo Saga, Takayoshi Ishimori, Yuji Nakamoto, Noriko Sato, Tatsuya Higashi, Takahiro Mukai, Hisataka Kobayashi, Junji Konishi
Published 2003-03-01

Radiolabeled Human Monoclonal Antibody 067-213 has the Potential for Noninvasive Quantification of CD73 Expression

by Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Gene Kurosawa, Yoshikazu Kurosawa, David Alexander, Hiroyuki Tsuda, Tsuneo Saga, Tatsuya Higashi
Published 2020-03-01

Efficacy Evaluation of Combination Treatment Using Gemcitabine and Radioimmunotherapy with 90Y-Labeled Fully Human Anti-CD147 Monoclonal Antibody 059-053 in a BxPC-3 Xenograft Mous...

by Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Mitsuru Koizumi, Yoshinori Ukai, Gene Kurosawa, Yoshikazu Kurosawa, Tsuneo Saga, Tatsuya Higashi
Published 2018-09-01

Preclinical Evaluation of the Acute Radiotoxicity of the α-Emitting Molecular-Targeted Therapeutic Agent 211At-MABG for the Treatment of Malignant Pheochromocytoma in Normal Mice

by Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Kotaro Nagatsu, Katsuyuki Minegishi, Noriko S. Ishioka, Hiroshi Ito, Keiichiro Yoshinaga, Tatsuya Higashi
Published 2019-07-01

Selective Targeting of Cancerous Mitochondria and Suppression of Tumor Growth Using Redox-Active Treatment Adjuvant

by Rumiana Bakalova, Severina Semkova, Donika Ivanova, Zhivko Zhelev, Thomas Miller, Tsuguhide Takeshima, Sayaka Shibata, Dessislava Lazarova, Ichio Aoki, Tatsuya Higashi
Published 2020-01-01

Preclinical Pharmacokinetic and Safety Studies of Copper-Diacetyl-Bis(N4-Methylthiosemicarbazone) (Cu-ATSM): Translational Studies for Internal Radiotherapy

by Hiroki Matsumoto, Yukie Yoshii, Atsumi Baden, Emi Kaneko, Hiroki Hashimoto, Hisashi Suzuki, Kazunori Kawamura, Ming-Rong Zhang, Tatsuya Higashi, Hiroaki Kurihara
Published 2019-09-01

Do TSH, FT3, and FT4 Impact BAT Visualization of Clinical FDG-PET/CT Images?

by Ryuichi Nishii, Shigeki Nagamachi, Youichi Mizutani, Tamasa Terada, Syogo Kiyohara, Hideyuki Wakamatsu, Seigo Fujita, Tatsuya Higashi, Keiichiro Yoshinaga, Tsuneo Saga, Toshinori Hirai
Published 2018-01-01