PPARα suppresses insulin secretion and induces UCP2 in insulinoma cells

by Karen Tordjman, Kara N. Standley, Carlos Bernal-Mizrachi, Teresa C. Leone, Trey Coleman, Daniel P. Kelly, Clay F. Semenkovich
Published 2002-06-01

Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding.

by Kari T Chambers, Zhouji Chen, Peter A Crawford, Xiaorong Fu, Shawn C Burgess, Ling Lai, Teresa C Leone, Daniel P Kelly, Brian N Finck
Published 2012-01-01

PGC1α plays a critical role in TWEAK-induced cardiac dysfunction.

by Jianru Shi, Bingbing Jiang, Yiling Qiu, Jian Guan, Mohit Jain, Xin Cao, Michael Bauer, Lihe Su, Linda C Burkly, Teresa C Leone, Daniel P Kelly, Ronglih Liao
Published 2013-01-01

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

by Teresa C Leone, John J Lehman, Brian N Finck, Paul J Schaeffer, Adam R Wende, Sihem Boudina, Michael Courtois, David F Wozniak, Nandakumar Sambandam, Carlos Bernal-Mizrachi, Zhouji Chen, John O Holloszy, Denis M Medeiros, Robert E Schmidt, Jeffrey E Saffitz, E Dale Abel, Clay F Semenkovich, Daniel P Kelly
Published 2005-04-01