Use of synthetic isoprenoids to target protein prenylation and Rho GTPases in breast cancer invasion.

by Min Chen, Teresa Knifley, Thangaiah Subramanian, H Peter Spielmann, Kathleen L O'Connor
Published 2014-01-01

Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24

by Sandy Y. Chang, Sarah E. Hudon-Miller, Shao H. Yang, Hea-Jin Jung, John M. Lee, Emily Farber, Thangaiah Subramanian, Douglas A. Andres, H.Peter Spielmann, Christine A. Hrycyna, Stephen G. Young, Loren G. Fong
Published 2012-06-01