Thomas C. Südhof

Südhof in 2024 Thomas Christian Südhof (; born December 22, 1955), ForMemRS, is a German-American biochemist known for his study of synaptic transmission. Currently, he is a professor in the school of medicine in the department of molecular and cellular physiology, and by courtesy in neurology, and in psychiatry and behavioral sciences at Stanford University.

Südhof, James Rothman and Randy Schekman are the 2013 Nobel Prize in Physiology or Medicine laureates for their work on vesicle trafficking.

Thomas Südhof retracted [https://www.pnas.org/doi/10.1073/pnas.2403021121 Lin et. al. 2023] research paper published in PNAS from his lab due to [https://pubpeer.com/publications/DAF32F6DB6C166337E5381F769AE52 falsified data], and since mid-2022, [https://pubpeer.com/search?q=Thomas+C.+S%C3%BCdhof PubPeer] commenters including Elisabeth Bik have flagged more than 40 of Südhof’s papers, which explore how neurons communicate across synapses. Provided by Wikipedia
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  1. 1
    Truth in Science Publishing: A Personal Perspective.
    by Thomas C Südhof
    Published 2016-08-01
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    Article
  2. 2
    The Perils of Navigating Activity-Dependent Alternative Splicing of Neurexins
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    Article
  3. 3
    Latrophilin GPCR signaling mediates synapse formation
    by Richard Sando, Thomas C Südhof
    Published 2021-03-01
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    Article
  4. 4
    LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses
    by Alessandra Sclip, Thomas C Südhof
    Published 2020-01-01
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    Article
  5. 5
    Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum
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    Article
  6. 6
    Neurexins regulate presynaptic GABAB-receptors at central synapses
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  7. 7
    Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction.
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  8. 8
    Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles.
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    Article
  9. 9
    Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch.
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    Article
  10. 10
    A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release
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    Article
  11. 11
    Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
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  12. 12
    Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion.
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  13. 13
    beta-Neurexin is a ligand for the Staphylococcus aureus MSCRAMM SdrC.
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  14. 14
    Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.
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  15. 15
    Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism
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  16. 16
    Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1
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  17. 17
    Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins
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  18. 18
    Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq
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  19. 19
    A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in mammalian brain neurons
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