COP1, a negative regulator of photomorphogenesis, positively regulates plant disease resistance via double-stranded RNA binding proteins.

by Gah-Hyun Lim, Timothy Hoey, Shifeng Zhu, Marion Clavel, Keshun Yu, Duroy Navarre, Aardra Kachroo, Jean-Marc Deragon, Pradeep Kachroo
Published 2018-03-01

RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations

by Marcus M. Fischer, V. Pete Yeung, Fiore Cattaruzza, Rajaa Hussein, Wan-Ching Yen, Christopher Murriel, James W. Evans, Gilbert O’Young, Alayne L. Brunner, Min Wang, Jennifer Cain, Belinda Cancilla, Ann Kapoun, Timothy Hoey
Published 2017-11-01

Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs.

by Mingjun Zhang, Michael Haughey, Nai-Yu Wang, Kate Blease, Ann M Kapoun, Suzana Couto, Igor Belka, Timothy Hoey, Matthew Groza, James Hartke, Brydon Bennett, Jennifer Cain, Austin Gurney, Brent Benish, Paola Castiglioni, Clifton Drew, Jean Lachowicz, Leon Carayannopoulos, Steven D Nathan, Jorg Distler, David A Brenner, Kandasamy Hariharan, Ho Cho, Weilin Xie
Published 2020-01-01