Chemotherapy‐Enriched THBS2‐Deficient Cancer Stem Cells Drive Hepatocarcinogenesis through Matrix Softness Induced Histone H3 Modifications

by Kai‐Yu Ng, Queenie T. Shea, Tin‐Lok Wong, Steve T. Luk, Man Tong, Chung‐Mau Lo, Kwan Man, Jing‐Ping Yun, Xin‐Yuan Guan, Terence K. Lee, Yong‐Ping Zheng, Stephanie Ma
Published 2021-03-01

Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer

by Man Tong, Tin-Lok Wong, Hongzhi Zhao, Yuanyuan Zheng, Yu-Nong Xie, Cheuk-Hin Li, Lei Zhou, Noélia Che, Jing-Ping Yun, Kwan Man, Terence Kin-Wah Lee, Zongwei Cai, Stephanie Ma
Published 2021-08-01

The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progression

by Nicole Pui Yu Ho, Carmen Oi Ning Leung, Tin Lok Wong, Eunice Yuen Ting Lau, Martina Mang Leng Lei, Etienne Ho Kit Mok, Hoi Wing Leung, Man Tong, Irene Oi Lin Ng, Jing Ping Yun, Stephanie Ma, Terence Kin Wah Lee
Published 2021-02-01

PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation

by Lok Hei Chan, Lei Zhou, Kai Yu Ng, Tin Lok Wong, Terence K. Lee, Rakesh Sharma, Jane H. Loong, Yick Pang Ching, Yun-Fei Yuan, Dan Xie, Chung Mau Lo, Kwan Man, Benedetta Artegiani, Hans Clevers, Helen H. Yan, Suet Yi Leung, Stéphane Richard, Xin-Yuan Guan, Michael S.Y. Huen, Stephanie Ma
Published 2018-10-01